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Magnetic nanoparticles have found application as MRI contrasting agents. Herein, chitosan thin films containing super-paramagnetic iron oxide nanoparticles (SPIONs) are evaluated in magnetic resonance imaging (MRI). To determine their contrasting capability, super-paramagnetic nanoparticles coated with citrate (SPIONs-cit) were synthesized. Then, chitosan thin films with different concentrations of SPIONs-cit were prepared and their MRI data (i.e., r and r*) was evaluated in an aqueous medium. The synthesized SPIONs-cit and chitosan/SPIONs-cit films were characterized by FTIR, EDX, XRD as well as VSM with the morphology evaluated by SEM and AFM. The nanoparticle sizes and distribution confirmed well-defined nanoparticles and thin films formation along with high contrasting capability in MRI. Images revealed well-dispersed uniform nanoparticles, averaging 10 nm in size. SPIONs-cit's hydrodynamic size averaged 23 nm in diameter. The crystallinity obeyed a chitosan and SPIONs pattern. The in vitro cellular assay of thin films with a novel route was performed within Hek293 cell lines showing that thin films can be biocompatible.

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Background/aim: Infertility is defined as the inability to conceive after at least 1 year of unprotected intercourse. In about one third of infertile couples, a male factor is the primary problem. Thus, the present study aimed to determine the most common risk factors for male infertility in Iranian men. Materials and methods:This case-control study included 268 men attending an infertility clinic in Shiraz, Iran. In this study, 161 fertile men were compared with 108 infertile ones regarding risk factors such as smoking habits, drug consumption, hernia, varicocele, job, and BMI. The data were analyzed using logistic regression analysis and t-test. Results:The mean age of the fertile and infertile participants was 37.5 ± 7 and 36.3 ± 10, respectively. Our findings demonstrated a statistically significant relationship between male infertility and hernia, varicocele, taking ranitidine, job, and BMI. With an increase of 1 cigarette per day, there was a 1% decrease in the motility of the sperm. Moreover, with an increase of 1 year of cigarette smoking, 800,000 sperm are lost. Conclusion:The results revealed varicocele and hernia as the most common risk factors in men attending the infertility clinics in Shiraz. In addition, strenuous work could cause testicular injury.

Background: This study is part of the national survey of the epidemiology of psychiatric disorders in Iranian children and adolescents (IRCAP), aiming to survey the prevalence of child and adolescent psychiatric disorders in Kermanshah and its outskirts. Objectives: This study aimed to assess the child and adolescent mental health status in the Kermanshah Province of Iran. Methods: A representative randomized sample of 993 urban and rural children aged 6 to 18 (349 aged 6 - 9 years, 333 aged 10 - 14 years, and 311 aged 15 - 18 years) participated in a cross-sectional study to be screened for psychiatric disorders using the Persian version of K-SADS-PL. In addition, a demographic questionnaire was completed by the participant's parents. Results: According to DSM-IV, out of 993 participants, 114 (11.5%) had at least a kind of childhood psychiatric disorder. The highest rate of psychiatric disorders was in 10 to 14-year-old children (n = 43; 12.9%; 95% CI = 9.7 - 16.9). The most common psychiatric disorders were anxiety disorders (n = 65; 6.5%; 95% CI = 5.2 - 8.3), followed by behavioral disorders (n = 30; 3%; 95% CI = 2.1 - 4.3), neurodevelopmental disorders (n = 22; 2.2%; 95% CI = 1.1 - 2.7), and depressive disorders (n = 17; 1.7%; 95% CI = 1.1 - 2.7). Conclusions: Compared to other pediatric diseases, the psychiatric disorder's prevalence is pretty high among the youths of Kermanshah Province. Therefore, child and adolescent mental health should be a priority for the youth healthcare system in Kermanshah.