what has demanded from practical applications for collecting the big data. Therefore, to resolve the cost issues, a R2R printing foundry has been highly attracted because the flexible passive components (such as sensor electrodes, capacitors, and antenna) are able to integrate with their flexible active components (such as display, processor, [3] transponder, [4] analogto-digital converter (ADC), [5] operation amplifier [6]) through a R2R inline printing system. [7] However, although sensor electrodes, [8] capacitors, [9] antenna, [10] and thin film transistor (TFT) active matrix-based display [11] have been successfully printed via R2R printing method, they cannot integrate with flexible active components yet through the R2R inline printing system so far. The major reason in difficulty of inline integration of R2R printed passive components with the flexible active components was mainly originated from the incompatibility between printing and vacuum deposition techniques, employed in manufacturing those flexible active components. Although a printing process was incorporated with the vacuum deposition methods in fabricating those flexible active components, it was limited to fabricating only the semiconducting layers, [12] and lacked the scalability required for practical mass production. Thus, those hybrid vacuum deposition and printing processes cannot be incorporated into the R2R printing foundry. To establish the R2R printing foundry concept, the design rule that encompasses physical dimensions and electrical parameters of the fully printed devices should be first established. The design rule in a semiconductor fabrication plant-referred to as the foundry-is a compromised rule between circuit design engineers and process engineers to provide the geometry of an integrated circuit layout with an acceptable cost. However, unlike the Si-chip foundry, the printed devices' physical dimensions and electrical parameters are variable to the rheological parameters of the electronic inks, the web tension, printing speed, and overlay printing registration accuracy (OPRA) of employed R2R printer. Therefore, the design rule of the R2R printing foundry (Figure 1a) should be always comprising characteristics of both employed ink and R2R printer to prove that the R2R printed complementary metal-oxide-semiconductor (CMOS)-based active
spanning almost the entire range of commercial products in industry, agriculture, and medicine. That is why the development of roll-to-roll (R2R) printed passive RFID tags is extremely attractive, due to perceived cost reduction achievableindeed, this has been the driving force for the realization of the penny RFID tag for the ID and the authentication without incorporating any encryption engine. SuchThe ORCID identification number(s) for the author(s) of this article can be found under https://doi.org/10.1002/admt.201900935.Printed electronics has been received a great deal of attention in the last two decades with a primary focus being on the use of organic semiconductors for the inexpensive and flexible electronic devices. [1][2][3][4][5][6][7][8] Applications such as flexible displays and passive radio frequency identification (RFID) tags have been widely touted in this regard. In particular, the roll-to-roll (R2R) printed passive 13.56 MHz RFID tag has a very competitive advantage for ID and authentication to prevent counterfeits over the traditional Si-chip based one because the low cost is always the first priority to be considered to authenticate genuine products
Introduction: Older adults continue to receive potentially inappropriate medications necessitating the need for medication optimization, by deprescribing. To ensure a holistic approach to deprescribing, it is essential to understand the perception of older adults towards deprescribing. This study aimed to assess the attitude of older ambulatory patients towards deprescribing and to identify factors predicting their willingness to deprescribe. Methods: A cross-sectional survey was conducted in central Nepal between March and September 2019 among 385 older ambulatory care patients (aged ⩾65 years) who were taking at least one regular medicine. The perception of patients towards deprescribing was assessed using the revised Patients’ Attitudes Towards Deprescribing (rPATD) questionnaire via a face-to-face interview method. Descriptive statistics were performed to describe patients’ characteristics and their attitudes towards deprescribing. A multivariate logistic regression analysis was used to determine predictors of the willingness of older ambulatory patients towards deprescribing. Results: The median [interquartile range (IQR)] age of patients was 72 (8) years. Nearly three in five patients (64.9%) had hypertension, with 11.2% having polypharmacy. More than half of the patients (57.4%) would be willing to stop one or more of their regular medicines if their doctor said it was possible to do so. Regression analysis showed that age [odds ratio (OR) 0.946; 95% CI 0.913, 0.981; p = 0.003] and concerns about stopping medicine score (OR 0.541; 95% CI 0.334, 0.876; p = 0.013) were predictors of the willingness of the older patients towards deprescribing. Conclusion: One in two older ambulatory care patients in Nepal would be willing to have one or more of their medicines deprescribed. The factors predicting their willingness to deprescribe are their age and concerns about stopping medicines. Clinicians should consider discussing the possibility of deprescribing with older patients for the prevention of potential medication-related harms. Plain Language Summary What do older Nepalese patients think about withdrawal or dose reduction of an inappropriate medication? Introduction: Research suggests that older adults (aged ⩾65 years) continue to receive medications that have the potential for harm rather than a benefit. This necessitates the need for withdrawal or dose reduction of such inappropriate medications, the process known as deprescribing. Understanding what older patients think about this process could be a stepping-stone to the general approach for its implementation. Data on deprescribing is lacking from Nepal. Therefore, we designed a survey to explore the attitude of older patients towards deprescribing and factors that could predict their willingness to deprescribe. Methods: This study was conducted between March to September 2019 among 385 older patients who were taking at least one regular medicine and were visiting selected hospitals of Nepal for outpatient services. We performed a face-to-face interview to assess the attitude of patients towards deprescribing using a validated tool called revised Patients’ Attitudes Towards Deprescribing (rPATD) questionnaire that quantified the response through scoring. The data were subjected to statistical analysis to determine the attitudes of Nepalese older patients towards deprescribing and to develop a model to predict their willingness to deprescribe. Results: The average age of the participant was 72 years with 65% having hypertension and 11% using more than five medications. Our data suggested that one in two older Nepalese patients would be willing to stop one or more of their regular medications if their doctors said it was possible to do so. Their willingness to deprescribe could be predicted from their age and concerns about stopping medications. Conclusion: Clinicians should consider discussing the possibility of deprescribing with older patients for the prevention of potential medication-related harms.
Roll‐to‐roll (R2R) printed electronic devices have great advantages for developing large scale flexible and disposable devices when compared to current Si‐based technology. For practical realization of these advantages, however, R2R printed devices need to surmount device functionality limitations, most urgently high‐power dissipation and poor device stability. To resolve both imperative challenges at once, herein, an all R2R printed complementary metal‐oxide‐semiconductor (CMOS) 1‐bit code generator with spin‐coated multilayer encapsulation method is developed. In order to print CMOS devices by an all‐R2R gravure printing method, electrical amphoteric property of the single walled carbon nanotube (SWCNT) is utilized to fabricate both p‐type and n‐type SWCNT based thin film transistors (TFTs). In addition, printable encapsulating polymeric materials (CYTOP and FG‐3650) are developed to effectively prevent H2O permeation. The resulting CMOS 1‐bit code generator is able to continuously operate for 2 h under ambient conditions without any variation in output voltage and frequency.
We introduced a FGO–PVDF composite as an encapsulation layer to prove the reliability of PEDOT:PSS thermistors under high-humidity conditions to realize an NFC-enabled smart label for monitoring time-temperature history of a food item along the cold chain.
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