Magnetic resonance (MR) imaging-guided biopsy is one of the most exciting and rapidly developing areas in radiology. MRI offers the best demonstration of many pathological lesions because of its multiplanar and three-dimensional (3D) capabilities, excellent soft tissue contrast, and high spatial resolution. This article reviews the state of the art in percutaneous MR-guided biopsies. Indications, technical aspects for optimal performance of the procedures, and specific advantages and disadvantages are discussed. Special emphasis is placed on the use of open MR scanners, which dramatically increases patient accessibility for MR-guided biopsies. Specific topics addressed include MR-guided biopsy of the brain, the head and neck, and of abdominal, breast, and musculoskeletal regions.
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