We report a facile and efficient preparation of a NIR-triggered micelle system for a drug vehicle.

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The performances of polymer solar cells follow the trend of the acid dissociation constant of acid derivatives.

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Perylene diimide with ammonium oxide as a terminal group (named PDIN-O) is a well-known cathode interlayer in conventional-type organic solar cells (OSCs). Since naphthalene diimide exhibits a lower LUMO level than perylene diimide, we chose it as a core to further control the LUMO level of the materials. Small molecules (SMs) produce a beneficial interfacial dipole by the end of ionic functionality at the side chain of naphthalene diimide. With the active layer based on a nonfullerene acceptor (PM6:Y6BO), the power conversion efficiency (PCE) is enhanced by utilizing SMs as cathode interlayers. We discovered that the inverted-type OSC with naphthalene diimide with oxide as a counteranion (NDIN-O) shows poor thermal stability, which can cause irreversible damage to the interlayer−cathode contact, leading to poor PCE (11.1%). To overcome the disadvantage, we introduce NDIN-Br and NDIN-I with a higher decomposition temperature. An excellent PCE of 14.6% was achieved with the device based on NDIN-Br as an interlayer, which is almost the same as the PCE of the ZnO-based device (15.0%). The device based on NDIN-I without the ZnO layer exhibits an improved PCE of 15.4%, which is slightly higher than the ZnO-based device. The result offers a replacement of the ZnO interlayer, which is necessary to carefully manage the sol−gel transition by annealing temperatures as high as 200 °C and leading to low-cost manufacture of OSCs.

In this article, a drug delivery system with a near-infrared (NIR) light-responsive feature was successfully prepared using a block copolymer poly(ethylene oxide)-b-poly(glycidyl methacrylate)-azide (PEO-b-PGMA-N3) and a cross-linker containing a Se-Se bond through “click” chemistry. Doxorubicin (DOX) was loaded into the core-cross-linked (CCL) micelles of the block copolymer along with indocyanine green (ICG) as a generator of reactive oxygen species (ROS). During NIR light exposure, ROS were generated by ICG and attacked the Se-Se bond of the cross-linker, leading to de-crosslinking of the CCL micelles. After NIR irradiation, the CCL micelles were continuously disrupted, which can be a good indication for effective drug release. Photothermal analysis showed that the temperature elevation during NIR exposure was negligible, thus safe for normal cells. In vitro drug release tests demonstrated that the drug release from diselenide CCL micelles could be controlled by NIR irradiation and affected by the acidity of the environment.

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