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The paper presents a model predictive approach for evaluating network lifetime and cluster head selection for a wireless sensor network. The dynamic parameters of a wireless sensor network are collected using Smart Mesh IP Power and performance calculator. The study considers a machine learning approach to combine clustering with the optimal routing protocol. The hop depth, advertising, number of Motes, backbone, routing, reporting interval, payload size, downstream frame size, supply voltage, and path stability are the predictors, and the current consumption, data latency, and build time are the response variables to establish the models for estimating the power and performance of the network. The remaining energy in each node, distance from the base station, and data transmission rate are the predictors, and the priority of the cluster head is the response variable to establish models for achieving an optimal routing path in a wireless sensor network. The standard tree, Support Vector Machine, Ensemble, and Gaussian process regression models for lifetime estimation are analyzed in comparison with the Smart Mesh IP tool, and the models for cluster head selection are investigated in comparison with ANFIS based models. This novel approach concentrates on the effect of various dynamic parameters on network lifetime prediction.