The article provides an overview of drugs for use in dental practice. The issue of diseases of the oral mucosa remains relevant at the present time. There are various methods and drugs for the treatment of inflammatory diseases of the oral cavity. The purpose of this work was to study the current state of research in the development of the composition and technology of external soft dosage forms. In this regard, the promising area are phytocompositions that have been used successfully for a long time. However, currently, the drug Tizol, an aquacomplex of titanium glycerosolvate, is of great interest, which, in addition to positive characteristics, has certain properties of a penetrator, which is very important when used in dentistry.
Relevance: red lichen planus refers to a long, protracted disease with a chronic course. There are a lot of root causes, it is quite difficult to differentiate them. Therefore, pharmacotherapy of this pathology is reduced to the appointment of local drugs that have only symptomatic effects that help accelerate the healing of the oral mucosa.Purpose – to study reparative regeneration based on the analysis of clinical and cytological examination on the background of the appointment of various methods of pharmacotherapy.Materials and methods: all patients were divided into two groups using simple randomization: in patients of the first group, betamethasone B was used to treat erosive-ulcerative lesions, which were delivered to the lesion using Tisol, which has conductive transcutaneous activity, using the sandwich technique. The second group of patients used the drug delivery system in the form of a film, which fixed betamethasone B in the lesion area.Results: were evaluated before treatment, on day 7 and 14. The area and intensity of healing of the oral mucosa were determined, a qualitative and quantitative analysis of cytograms was carried out, which characterizes the dynamics of reparative regeneration of erosions and ulcers.Conclusion: based on the obtained clinical and laboratory data, it can be concluded that it is advisable to include betamethasone applications in the pharmacotherapy of patients with erosive and ulcerative forms of lichen planus. However, preference should be given to the method of layer-by-layer application of betamethasone B in combination with Tezol.
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