Aim. To study standardized all-cause mortality and cardiovascular mortality (or deaths due to diseases of the circulatory system) in Irkutsk and Moscow including assessment in gender and age subgroups. Material and methods. To compare mortality in the two cities data of Federal State Statistics Service were used with calculation of coefficients of mortality adjusted for European age pattern. Results: Age-standardized indices of mortality per 100,000 of population were significantly lower in Moscow as compared to Irkutsk in the entire sample (697.6 vs 1157.8; p<0.00001), in men (904.0 vs 1364.3; p<0.00001) and in women (535.1 vs 822.7; p<0.00001), and also in all age subgroups above 25 years. Cardiovascular diseases were dominated in the mortality patterns of the compared cities: 47% in Irkutsk, 64% in Moscow. Chronic forms of ischemic heart disease (47.9% in Irkutsk and 45.9% in Moscow) and cerebrovascular diseases (15.9% in Irkutsk and 16.7% in Moscow) were prevalent. There were significant distinctions in death rates encoded in such headings as: "Other forms of acute ischemic heart disease", "Atherosclerotic heart disease", "Cerebral atherosclerosis", "Hypertensive encephalopathy", and "Unspecified cardiomyopathy". Conclusion. Irkutsk had higher standardized coefficients of all-cause and cardiovascular mortality as compared to Moscow in the total population, in men and in women and in majority of age subgroups. This can be explained by economic, social and climatic factors.
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