Ultrawideband electromagnetic pulses with high amplitude and short duration are reported to affect several aspects of cell physiology. They are usually delivered to the living material through electrodes in small dedicated chambers. Here we showed, using a totally different experimental setup, that radiated EM pulses illuminating the living material through a specialized antenna (without any direct contact) are able to trigger a rapid release of ATP in cultured murine cells that was concomitant with a drop of intracellular AEC. Despite this rapid and strong response, we found that cell viability and clonogenicity were only slightly affected by the EMF exposure.
A complete pulsed power source, named MOUNA, is composed of a set of batteries, a DC/DC converter to charge four capacitors, four synchronized spark gap switches, a resonant transformer generating 600kV/265ns pulses, an oil peaking switch and a dipole antenna. This device must transmit waveforms with a wide frequency band and a high figure-of-merit.However, to radiate very high electric fields, the low gain of the dipole antenna is detrimental. The use of a directional antenna may improve performance really significantly focusing the radiation in a preferred direction. The main characteristics of the axial helical antenna (compactness, high gain on the axis, wideband spectrum and high impedance) make it an excellent candidate.In this paper, the first results concerning the design of the antenna (number of turns, size…), of a switch oscillator directly implemented at the output of the transformer are presented. The design of the novel radiating source composed of the MOUNA pulsed power source, the switch oscillator and the helical antenna is also described. The pulsed source and the oscillator contains in a volume of only 25 litres. Finally a CSTbased simulation is proposed to predict the performances of this wideband source.
In the class of emerging high power electromagnetic sources, a complete pulsed power source, named MOUNA (French acronym of "Module Oscillant Utilisant une Nouvelle Architecture") has been developed. This device must transmit waveforms with a wide frequency band and a high figure-of-merit. To improve the overall performance of the MOUNA system while maintaining its compact size, two approaches are being explored in the paper: the replacement of the dipole antenna by a helical antenna and its feeding signal influence. Helical antenna is cylindrical shape and relatively compact. It offers relatively good gain factor and directivity. The waveform delivered to the antenna is directly related to the amplitude of the radiated electric field. Therefore, different waveforms (step pulse, Gaussian pulse, bipolar pulse and damped sinusoid) are compared to point out the feed signal influence on the radiated electric field. Switch oscillators appear to be considered as interesting resonant sources for driving an antenna. The novel radiating source consists of a primary power source, a resonant transformer, a coaxial transmission line damped oscillator (also termed as coaxial resonator), and a helical antenna. This high voltage pulsed source is very compact (volume of only 2500 cc without the antenna). Our study aims at designing the antenna (number of turns, size…) and a coaxial damped oscillator directly implemented at the output of the transformer. A CST-based simulation is proposed to predict the performances of this wideband source.
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