Inflammation is a part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells or irritants. It is characterized by redness, swollen joints, joint pain, its stiffness and loss of joint function. Inflammation is currently treated by NSAIDs. Unfortunately these drugs cause increased risk of blood clot resulting in heart attacks and strokes. Therefore, the developments of potent anti-inflammatory drugs from the natural products are now under considerations. Natural products are rich source for discovery of new drugs because of their chemical diversity. A natural product from medicinal plants plays a major role to cure many diseases associated with inflammation. The conventional drug available in the market to treat inflammation produces various side-effects. In this present study anti-inflammatory potential of Nerium Oleander was investigated. Based on the resulted the ethonolic extract of the flowers showed the highest anti inflammatory activity. The increments in absorbance of test samples with respect to control indicated stabilization of protein i.e. inhibition of heat-induced protein (albumin) denaturation by Nerium oleander and reference drug diclofenac sodium.
Adsorption of Malachite Green (MG) on activated carbon obtained from Teak wood biomass has been investigated by batch adsorption method. The percentage removal of dye has been optimized by studying the initial concentration of the dye, adsorbent dosage, adsorption time and pH. The experimental data were found to be well fitted to Langmuir isotherm. The present study indicates that activated carbon obtained from Teak wood biomass is an effective adsorbent of MG dye. The prepared activated carbon was evaluated for antimicrobial activity against (Staphylococcus aureus, Escherichia coli and Aspergillus flavus, Aspergillus niger), using disc diffusion method and compared with standard antibacterial (Nitrofurantoin) and antifungal (Amphotericin B). Bacteria showing more activity than fungal strains.
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