Breath-holding spells are benign, paroxysmal events with apnea and postural tone changes after a crying episode in infants. The objective of this study was to investigate the pathologies in brain metabolite values in the absence of seizure in children with breath-holding spells by using magnetic resonance spectroscopy (MRS). Brain MRS examination was performed on 18 children with breath-holding spells and 13 neurologically normal children who were included as the control group. There was no significant difference in terms of N-acetyl aspartate (NAA), choline (Cho), creatine (Cr), and myoinositol (mI) levels and also in terms of NAA/Cr, Cho/Cr, and mI/Cr ratios between the patients and the control group (all P>0.05). Our study suggested that there is no permanent neuronal damage in patients with breath-holding spells. This result confirms the previous studies, which reported no permanent neuronal damage in patients with breath-holding spells.
The aim of this study was to examine the relationship between idiopathic carpal tunnel syndrome (CTS) and mean platelet volume (MPV) in patients older than 65 years old. The study included 48 patients, 92 hands (45 right/47 left) from 8225 patients who were consulted to electroneuromyography (ENMG) laboratory in January 2010 to December 2013. ENMG data, whole blood cell, erythrocyte sedimentation rate, C-reactive protein (CRP) levels of all patients were noted. In patient group MPV levels were significantly high (P=0.014). Although CRP levels were significantly elevated in patients, all CRP levels were in normal range. As a result, in patients older than 65 years increased MPV levels may be associated with CTS etiology and increased risk of cardiovascular disease.
ÖzetBu çalışmanın amacı 65 yaş üstü hastalarda idiopatik karpal tünel sendromu (KTS) ile ortalama trombosit hacmi (MPV) arasındaki ilişki varlığını araştırmaktır. Bu retrospektif çalışmaya hastanemiz ENMG laboratuvarına 2010 Ocak-2013 Aralık arasında başvuran 8225 hasta içerisinden 65 yaş üstündeki idiopatik KTS tanısı alan 48 hasta, 92 el (45 sağ/47 sol) alındı. Hastaların elektronöromyografi (ENMG) verileri, tam kan sayımı, eritrosit sedimantasyon oranı, C-reaktif protein (CRP) düzeyleri kaydedildi. Hasta grubunda MPV değeri kontrol grubunda göre anlamlı düzeyde yüksek bulundu (P=0.014). CRP değeri hasta grubunda anlamlı düzeyde daha yüksek (P=0.023) olmakla beraber tüm hasta ve kontrol grubunun CRP değerleri hastanemiz normal sınırı olan 0.5 değerinin altındaydı. Sonuç olarak 65 yaş üstü hastalarda artmış MPV düzeyi KTS oluşumunda rol oynayabileceği ve kardiovasküler risk artışı ile ilişkili olabileceğini düşündürmektedir. Anahtar kelimeler: Karpal tünel sendromu; ortalama trombosit hacmi
We present an adult female patient with Dyke-Davidoff-Masson syndrome with distinct features, and discuss neuroimaging findings some of which are unique to this syndrome.
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