S u m m a r y . In order to investigate the role of testosterone propionate (TP) on the antioxidant system of the rat testis, lipid peroxidation (LPX) and activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) of the testis of testosterone-treated and control rats were compared. The results indicate that T P administration to intact adult rats resulted in a significant decline in protein content of various subcellular fractions. This is accompanied with significant elevation in LPX levels of various subcellular fractions suggesting induction of oxidative stress. Activities of three enzymes related to the metabolism of superoxide radical (SOD) and hydrogen peroxide (CAT and GPx) of testis, were found to be significantly decreased in response to T P treatment. The role of testosterone in regulating testicular spermatogenesis through oxidative stress is discussed.
Sarcocystis spp. are a group of tissue cystforming coccidia which infect a vast range of animals as well as human beings. Found frequently in animal carcasses at slaughter, undermining their value, they have also been found associated with clinical disease. Dogs and cats are involved in the transmission. Studies in India point to a vast reservoir of infection with high prevalence rates in various livestock species. However, there is a glaring paucity of reports on the horse and Sarcocystis of the camel has remained totally unexplored so far. At least two different Sarcocystis spp. can parasitize each livestock host species. Experimental transmission studies have provided additional parameters for distinguishing the species. The clinical symptoms are generally non-specific and diagnosis in the living animal, by the presently available means, is almost impossible. Immunodiagnosis till now is beset with problem of cross-reactivity. Treatment with anti-coccidials presently tried do not seem satisfactory. Of the two zoonotic species with cattle-man and pig-man cycles, only the latter seems of some significance in India due to backyard pig-rearing and slaughter practices. It is a paradox that despite high prevalence of S. suihominis in pigs, reports of human cases are limited. This and some of the existing grey areas of information in the Indian context, have been highlighted as also possible directions for future research.
Crossbred calves (Bos taurus x Bos indicus) were repeatedly infested with the ixodid tick, Hyalomma anatolicum anatolicum. The parameters of engorgement, pre-oviposition period, oviposition period, engorged weight, egg batch weight, and per cent hatch of eggs all showed statistically significant differences between first to tenth infestation. Only the time to engorgement did not change. It is concluded that repeated infestations of this tick stimulate acquired resistance.
Theileria infection of Hyalomma ticks collected from three districts of Haryana was assessed in whole salivary glands by the methyl-green pyronin staining method. Of 1,662 ticks screened, 546 (32.8%) were found Theileria positive. Infection rate in 935 female ticks (36.9%) was more than that of 727 male ticks (27.6%). Density of Theileria infection (number of infected acini per infected tick) was also higher in female ticks. Theileria infection rate of ticks varied greatly in the three districts viz. only 12.0% in Rohtak, 25.8% in Hisar and 48.3% in Karnal. Per cent infection rate was high (63.7%) in ticks from indigenous cattle and low (18.6%) in those collected from buffaloes. However, the intensity of infection in infected ticks from cross-bred cattle was comparatively much higher. Frequency distribution of Theileria positive acini in infected ticks revealed a low density of infection per infected tick. This points to the largely stable endemic situation prevailing in Haryana. Only a single salivary acinus was found infected in 16.6% of the infected ticks, about 70% had up to 10 infected acini while only about 10% had over 25 infected acini per tick. The masses in acini presumed to be Theileria were confirmed by demonstrating parasitic masses on staining one of a pair of salivary glands and inoculating the suspension of the other half of the gland into two cross-bred cow calves which developed clinical signs and lesions typical of theileriosis.
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