The functional dynamics exhibited by cell collectives are fascinating examples of robust, synchronized, collective behavior in spatially extended biological systems. To investigate the roles of local cellular dynamics and interaction strength in the spatiotemporal dynamics of cell collectives of different sizes, we study a model system consisting of a ring of coupled cells incorporating a three-step biochemical pathway of regulated activator-inhibitor reactions. The isolated individual cells display very complex dynamics as a result of the nonlinear interactions common in cellular processes. On coupling the cells to nearest neighbors, through diffusion of the pathway end product, the ring of cells yields a host of interesting and unusual dynamical features such as, suppression of chaos, phase synchronization, traveling waves, and intermittency, for varying interaction strengths and system sizes. But robust complete synchronization can be induced in these coupled cells with a small degree of random coupling among them even where regular coupling yielded only intermittent synchronization. Our studies indicate that robustness in synchronized functional dynamics in tissues and cell populations in nature can be ensured by a few transient random connections among the cells. Such connections are being discovered only recently in real cellular systems.
Fine magnetic particles (sizeffi100 Å ) belonging to the series Zn x Fe 1Àx Fe 2 O 4 were synthesized by cold co-precipitation methods and their structural properties were evaluated using X-ray diffraction. Magnetization studies have been carried out using vibrating sample magnetometry (VSM) showing near-zero loss loop characteristics. Ferrofluids were then prepared employing these fine magnetic powders using oleic acid as surfactant and kerosene as carrier liquid by modifying the usually reported synthesis technique in order to induce anisotropy and enhance the magneto-optical signals. Liquid thin films of these fluids were prepared and field-induced laser transmission through these films was studied. The transmitted light intensity decreases at the centre with applied magnetic field in a linear fashion when subjected to low magnetic fields and saturate at higher fields. This is in accordance with the saturation in cluster formation. The pattern exhibited by these films in the presence of different magnetic fields was observed with the help of a CCD camera and was recorded photographically. r
Ferrofluids belonging to the series, Ni x Fe 1−x Fe 2 O 4 and Zn x Fe 1−x Fe 2 O 4 , were synthesized using cold co-precipitation. Liquid films of these ferrofluids were prepared by encapsulating the ferrofluids in between two optically smooth and ultrasonically cleaned glass plates. Magnetic field induced laser transmission through these ferrofluid films has been investigated. Magnetic field values can be calibrated in terms of output laser power in the low field region in which the variation is linear. This set up can be used as a cheap optical gaussmeter in the low field regime. Using the same set-up, the saturation magnetization of the sample used can also be calculated with a sample that is pre-characterized. Hence both magnetization of the sample, as well as applied magnetic field can be sensed and calculated with a precalibrated sample.
Ultra fine precursors for ferrofluid synthesis, belonging to the series, Ni x Fe 1-x Fe 2 O 4 (where 'x' varies from '0' to '0⋅ ⋅6' in steps of 0⋅ ⋅1), were synthesized. Ferrofluids based on these fine particles were prepared with oleic acid as surfactant and kerosene as carrier. Ferrofluidic thin films were made on glass substrates and magnetic field induced laser transmission was studied. The pattern exhibited by the films under the influence of a magnetic field was observed with the help of a CCD camera. The analysis of results confirms the chain formation of particles in the presence of an applied magnetic field and their saturation at higher applied fields. Keywords. Ferrofluids; nickel ferrite; field induced assembling; ultra fine particles.
In this Letter we numerically investigate the dynamics of a system of two coupled chaotic multimode Nd:YAG lasers with two mode and three mode outputs. Unidirectional and bidirectional coupling schemes are adopted; intensity time series plots, phase space plots and synchronization plots are used for studying the dynamics. Quality of synchronization is measured using correlation index plots. It is found that for laser with two mode output bidirectional direct coupling scheme is found to be effective in achieving complete synchronization, control of chaos and amplification in output intensity. For laser with three mode output, bidirectional difference coupling scheme gives much better chaotic synchronization as compared to unidirectional difference coupling but at the cost of higher coupling strength. We also conclude that the coupling scheme and system properties play an important role in determining the type of synchronization exhibited by the system.
Living systems are spectacular examples of spatiotemporally organized structures. During the development of complex organization there is dynamic equilibrium between the local and global processes acting at the intra-and intercellular levels in multiple space and time scales. Although in modelling studies such spatiotemporal systems can be described by different space-time scales and at many organizational levels, the experimental quantities measured and predictions useful for practical applications are at a macroscopic (coarser or averaged) level/scale; these are limited by the resolution of the measuring method and experimental protocol. In this work, we address whether the spatiotemporal collective dynamics exhibited by a multiscale system can discriminate between,or be borne out by,the coarse-grained and averaged measurements done at different spatial and temporal scales. Using a simple model of a ring of cells, we show that measurements of both spatial and spatiotemporal average behaviour in this multicellular ensemble can mask the variety of collective dynamics observed at other space-time scales, and exhibit completely different behaviours. Such outcomes of measurements can lead to incomplete and incorrect understanding of physiological functions and pathogenesis in multicell ensembles.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.