The article "ZNF797 plays an oncogenic role in gastric cancer" by D. Momenzadeh, S. Rahman Zadeh, M. Rezaei-Tavirani, A. Baradaran-Rafii, F. Ghasemvand and S. Heidari-Keshel published in Genetics and Molecular Research vol. 13 (4), pp. 8421-8427 in 2014, DOI: http://dx.doi.org/10.4238/2014.October.20.18, has been found to be substantially equal to the article "Role of SALL4 in the progression and metastasis of colorectal cancer" published in the Journal of Biomedical Science, vol. 20, p. 6 in 2013, DOI: 10.1186/1423-0127-20-6, by other authors. The corresponding author of the article published in Genetics and Molecular Research, Saeed Heidari-keshel, alerted our editorial staff about this situation and requested that the article should be retracted. After review and after contacting the authors, the editors of Genetics and Molecular Research have decided to retract the article. The authors and their institutions have been advised of this serious breach of ethics.
The article "Absolute quantification of free tumor cells in the peripheral blood of gastric cancer patients" by N. Bayat, M.M. Mokhtari, M. Rezaei-Tavirani, A. Baradaran-Rafii, S. Rahman Zadeh, S. Heidari-Keshel and F. Ghasemvand published in Genetics and Molecular Research vol. 13 (2), pp. 4425-4432 in 2014, DOI: http://dx.doi.org/10.4238/2014.June.16.1, has been found to be substantially equal to the article "Quantitative analysis of TEM-8 and CEA tumor markers indicating free tumor cells in the peripheral blood of colorectal cancer patients". published in International Journal of Colorectal Disease vol. 26 (10), pp. 1265-1270 in 2011, DOI: 10.1007/s00384-011-1230-8, by other authors. The corresponding author of the article published in Genetics and Molecular Research, Saeed Heidari-keshel, alerted our editorial staff about this situation and requested that the article should be retracted. The results are surprisingly similar, with the number of positive patients being almost the same, for example. After review and after contacting the authors, the editors of Genetics and Molecular Research have decided to retract the article. The authors and their institutions have been advised of this serious breach of ethics.
ABSTRACT. Gastric cancer remains the third most common cancer in the world. Metastatic disease is a major cause of death in about half of the patients; therefore, early diagnosis is crucial for successful outcome. This study applied a sensitive method for the detection of circulating tumor cells using specific tumor markers for early detection. A total of 80 blood samples from 40 patients and 40 age-matched healthy controls were collected for the study. Circulating mRNA levels of two tumor markers, tumor endothelial marker 8 (TEM-8) and carcinoembryogenic antigen (CEA) were evaluated using absolute quantitative real-time PCR assay in the Stratagene Mx-3000P real-time PCR system. GAPDH was used to normalize the data. TEM-8 and CEA were detected in patients' blood more than in controls, 22/40 vs 9/40, P = 0.005, and 30/40 vs 11/40, P = 0.008, respectively. The mRNA level of these markers in patients was significantly higher in comparison to normal controls (P = 0.018, 0.01). This panel showed an overall sensitivity of 64% and specificity of 73%. Statistical analysis for demographic variants did not show any significant differences. Both markers were detected more frequently and in significantly higher levels in blood samples of patients
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.