Four lactating cows were confined in metabolism stalls and each given a single oral dose of Hg(NO,),. For the next 10 days, all milk, urine and feccs from the four cows were collected and the mercury-203 content measured. Peak activity appeared in the milk 42 hr after ingestion of the radionuclide. The mercury-203 was eliminated by the cow with a biological half-time in milk of 131 hr. During the 10-day period after dosing, 75% of the ingested mercury-203 was excreted, with 0.08% recovered in the urine, 0.01 % in the milk, and the remainder in the feces. I n a companion study lactating COWS and calves were sacrificed a t various times after oral and intravenous administrations of mercury-203 and samples were collected to measure the tissue distribution of the radionuclide. The radiomercury was found distributed throughout the body after both intravenous and oral administrations, with the kidneys being the site of principal concentration. As indicated by the results of this study, inorganic radiomercury is sparingly absorbed from the intestinal tract of the dairy cow and the urinary system is the preferred route of excretion for the absorbed radiomercury.
A single oral dose of radioberyllium was administered to each of 4 cows to measure the transfer of radioberyllium to milk. Less than 0.002% of the ingested activity was recovered in the milk. The biological half-time as measured in the milk was 19 hr. Based on the results of this study, radioactive beryllium presents less radiological health hazard than do the other commonly released radionuclides.In a companion study, 1 lactating dairy COW was administered a single intravenous dose of radioberyllium and three calves were each given a single oral administration. The animals were sacrificed at various time intervals and samples collected for tissue distribution studies. The liver, kidney and skeletal system were found to accumulate most of the absorbed activity. The bone appeared to be the site of long-term deposition.
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