Mosquitoes transmit human diseases, causing millions and millions of deaths every year Mosquito borne diseases are one of the most serious public health problems in the developing countries. It can be controlled by using repellent, causing larval mortality and the development of resistance to chemical insecticides resulting in rebounding vectorial capacity. Plants may be alternative sources of mosquito control agents. Medicinal plants extracts of Vitex negundo, Azadirachta indica and Eucalyptus tereticornis were tested for their larvicidal activity against Culex quinquefasciatus. There are four different solvents were used (Petroleum-ether, Ethanol, Acetone and Hexane extract) for the preparation of crude extracts from the plant leaves. The larval mortality of second and third instar larvae C. quinquefasciatus after 24 hour to 48 hour of treatment were observed separately in control,100, 200,300,400 and 500 ppm concentrations of the leaf extract. The seven different solvent extract of Vitex negundo showed good larvicidal activity.
In general, drugs play a vital role in our day to day life to heal several diseases. However, higher doses of drug which initiates the side effect and leads to chronic disease. Among the drugs, this occupies a unique position because of its own functional properties. The methylxanthine derivatives are also largely consumed as a psychoactive alkaloid drug that includes Caffeine (C 8 H 10 N 4 O 2), Theophylline (C 7 H 8 N 4 O 2), Paraxanthine (C 7 H 8 N 4 O 2), Pentoxifylline (C 13 H 18 N 4 O 3), Theobromine (C 7 H 8 N 4 O 2), Aminophylline (C 16 H 24 N 10 O 4), and IBMX-3-Isobutyl-1-methylxanthine (C 10 H 14 N 4 O 2) and it has been stimulating particular parts of the nervous system in the human body. Especially this drug is consumed in the name of coffee more than 80% of people all over the world without knowingly or unknowingly the impact of caffeine. This paper deals with the effect of functional groups of methylxanthine having-NH 2 ,-C=O 2 ,-CONH 2 .
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