This symposium featured an international line-up of speakers presenting on the discovery and clinical development of novel therapeutic agents. The program included the Society of Medicines Research (SMR) Award Lecture, given by Dr. Betty Chang from Pharmacyclics on the discovery and development of the marketed drug ibrutinib, as well as talks, several representing first U.K. disclosures, on Toll-like receptor 7 (TLR7) agonists, Na v 1.
Collingwood and Andrew Ratcliffe, focused on kinase inhibitors from early research to clinic. Topics included kinase inhibitor design, translating kinase selectivity profiles into early safety guidance, and the discovery and early development of kinase inhibitors in the therapeutic areas of inflammation, pulmonary arterial hypertension and oncology.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.