BackgroundToxoplasmosis is one of the common worldwide parasitic zoonosis due to Toxoplasma gondii (T. gondii). Toxoplasmosis during pregnancy can result in fetal and neonatal death or various congenital defects. The aim of this study was to assess the seroprevalence and risk factors of T. gondii infection in pregnant women following antenatal care (ANC) services at Bobo Dioulasso.MethodsA cross-sectional study was conducted enrolling a sample of 316 pregnant women attending ANC at centers for maternal and child health of Bobo-Dioulasso town from March 2013 to February 2014. Data on socio-demographic and potential risk factors were collected from each study participant using structured questionnaire through face-to-face interview. Moreover, venous blood specimens were collected and tested for IgM and IgG anti-T. gondii antibodies by enzyme-linked immunosorbent assay and enzyme linked fluorescent assay, respectively. Multivariable logistic regression modeling was used to identify the potential predictor variables for T. gondii infection.ResultsThe overall seroprevalence for T. gondii infection was 31.1% (98/316). All the pregnant women were positive for IgG anti-bodies exclusively. Multivariable logistic regression analysis showed that having at least a secondary education level (AOR = 2.23; 95% CI: [1.04–4.63]); being urban resident (AOR = 2.81; 95% CI: [1.24–6.86]) and the consumption of meat combination (pork + beef + mutton + wild meat + poultry) (AOR = 4.00; 95% CI: [1.06–15.24]) were potential risk factors of T. gondii infection.ConclusionToxoplasmosis is frequent in pregnant women and studies that show incidence of T. gondii among the neonates have to be done to introduce routine antenatal screening program to control congenital toxoplasmosis. There is the need for preventive measures such as education of pregnant women about the transmission routes and prevention methods of toxoplasmosis at ANC clinics.
Aims: To analyze phenolic compounds and evaluate antifungal activity of methanolic and ethanolic extract's from Cymbopogon citratus against Fusarium graminearum and Fusarium oxysporum sp tulipae. Study Design: Activity directed antifungal activity, total phenolic compounds determination, total antioxidant determination and High Performance Liquid Chromatography (HPLC) phenolic compounds analysis of extract's from Cymbopogon citratus using in vitro methods.
Introduction:The tumours of skin adnexal are rare and very often benign. Because of their large diversity they caused some diagnose and classification problems. They are tumours of ten mixed up with other skin tumours. The objective of this study was to study the histopathological and epidemiological profile of the benign skin adnexal tumours in Ouagadougou and to classify them according to the differenciation type in order to well know them and improve their treatment. Methodology: We conducted a retrospective study on the period of sixteen years going from 1 st January 1998 to 31 December 2013. This study interested all cases of benign skin adnexal tumours histologically confirmed (diagnosed) in the three pathology laboratories of the Ouagadougou town. Results: We collected sixty cases of skin adnexal tumours on the total of 763 cases of skin tumours representing 7.8%. The benign tumours represented 86 % of the adnexal tumour cases. These tumours were occurred in the relatively young age and were preferentially located on the head (cephalic) extremity. On the histological plan, the hair follicle tumours were more frequent (42.5%) followed by sweat gland tumours (30.5%) and sebaceous gland tumours (27%). Conclusion: The annex tumours are majoritary benign occurring often on the head extremity and dominated by the hair follicle tumours.
Aims: We aimed at identifying the high-risk HPV genotypes associated with high-grade dysplastic cervical lesions in Burkina Faso. The available vaccines to Burkina Faso only protect against two high risk HPV genotypes: HPV 16 and 18. Are the genotypes identified in the high-grade precancerous lesions in this survey covered by the available vaccines? Methods: The detection and genotyping of high-risk HPV have been conducted based on 118 formalin-fixed and paraffin-embedded archived tissues using the "HPV Genotypes 14 Real-TM Quant" (Sacace biotechnologies ® , Italy) kit allowing for the detection of fourteen high-risk HPV genotypes: HPV 16, 31, 18, 39, 45, 59, 33, 35, 56, 68, 51, 52, 58 and 66. Results: The prevalence of high-risk HPV infections was 48.8% based on the appropriate PCR results (21/43). The most common HPV genotypes were HPV 39 (21.7%), * Corresponding author.C. Ouédraogo et al.
197HPV 35 (13.0%) and HPV 45 (13.0%). Two cases of multiple infections between HPV 39 -45 and HPV 39 -59 have been observed. HPV 16 was not detected in this study. Conclusions: We noted a high prevalence rate for HPV 39, HPV 35 and HPV 45, which are not covered by the commercial vaccines. We also found that the prevalence of HPV 18 was very low in this study and HPV 16 was not detected.
Background: Group B Streptococcus (GBS) or Streptococcus agalactiae, which asymptomatically colonizes the female genital tract, is one of the leading causes of septicemia, meningitis and pneumonia in neonates. This study was conducted in Bobo Dioulasso, Burkina Faso to determine the prevalence of GBS colonization among pregnant women. Methods: Six hundred and eleven (611) pregnant women were screened for GBS colonization between July and December 2016. Vaginal swab samples were aseptically collected from the subjects after oral informed consent. Standard microbiological methods were used to isolate and identify GBS isolates. The antibiotic susceptibility profile of GBS isolates was assessed using the Kirby-Bauer disk diffusion method. Results: Colonization prevalence was 6.05%. No risk factors associated with the carriage rate was statistically identified. All isolates were susceptible to Amoxicillin, Ampicillin, Cefotaxime, Levofloxacin, Vancomycin and Nitrofurantoin. Resistance to antibiotics was found for erythromycin (35.14%), lincomycin (16.22%) and penicillin G (10.81%). Conclusion: Although a low carriage (6.05%) rate and isolates were susceptible to many antibiotics found in this study, a policy of systematic screening of pregnant women at least in the third trimester must be promoted.
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