Background: To study drug prescription pattern in dental OPD of Government Dental College and Hospital. Methods: 100 prescriptions were screened & analyzed as per the study parameters from OPD of Government Dental College & Hospital, Aurangabad. Groups of drugs commonly prescribed, like antibiotic, analgesics & others prescription were recorded. Results: Most common groups of drugs prescribed by dental surgeons were NSAIDs, antimicrobials, antiseptics and multivitamins. NSAIDs- 86%; Antimicrobials- 85%; Antiseptics- 8.6%; Multivitamins- 12.3%. The average number of drugs prescribed per patient was 3 and the average number of antimicrobial prescribed per patient was 1. Conclusions: For rational prescribing of drugs there is a need of mass-awareness amongst dental surgeons about the good prescribing by following 6 steps of WHO program on rational use of drugs. [Int J Basic Clin Pharmacol 2013; 2(1.000): 69-70
Background: To study drug utilization of anticancer drugs in cancer outpatient department (OPD) of Government Medical College, Aurangabad. Methods: Five hundred and twelve prescription records were screened and analyzed as per the study parameters from cancer OPD of Government Medical College and Hospital, Aurangabad. Commonly used anticancer drugs were recorded; furthermore, different types of carcinomas were noted. Results: Age group of patients was in between 30 and 70, 267 were females and 245 were male patients. The most common type of carcinoma was carcinoma of the breast (17.9%). Carboplatin was the most commonly used anticancer drug (26.56%). The average number of anticancer drugs received per patient was three. Conclusion: WHO suggested drug utilization studies are needed in every health care setting. For a developing country like India, National Drug Policy and Drugs and Therapeutic Committee are a must.
Patients with type II diabetes mellitus are usually dyslipidemic, even when under relatively good glycaemic control. Furthermore type 2 diabetes is an important risk ABSTRACT Background: Statins are the first choice in the treatment of dyslipidemia, commonly atorvastatin. Pitavastatin is a newer statin with more potency, less drug interactions and many added advantages considering the longevity of treatment required for dyslipidemia. The objective of this study was to evaluate the efficacy and safety of pitavastatin versus atorvastatin in dyslipidemic patients associated with hypertension, diabetes and/or coronary artery disease. Methods: A prospective, comparative, randomized, controlled, double blind, clinical trial was designed. Total 100 eligible subjects were randomised into 1:1 ratio to receive pitavastatin 4 mg once daily and atorvastatin 20 mg once daily for period of 8 weeks. Evaluation was scheduled at 4 week and 8 week. The efficacy assessment included percentage change from baseline in various lipid parameters like low density lipoprotein cholesterol (LDLC), total cholesterol (TC), high density lipoprotein cholesterol (HDLC), triglycerides (TG), and LDLC/HDLC ratio. Results: Analysis of data showed a significant improvement in all lipid parameters within both therapeutic groups. The difference in LDLC, TC and TG levels was not statistically significant between the two treatment groups after 8 weeks of therapy. However, significant improvement was seen in HDLC and LDLC/HDLC ratio with pitavastatin as compared to atorvastatin at the end of the study. Both were well tolerated. Conclusions: With better HDLC levels, in addition to comparable efficacy and good tolerability of pitavastatin, as compared to atorvastatin, could be considered as good alternative for treatment of dyslipidemia.
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