Introduction: Recurrent non-immune fetal hydrops (NIH) has been reported in the literature but is a rare entity, with fewer than 6 reported cases so far. It has been postulated to be related to a recessive gene. Clinical Picture: We report a case of recurrent fetal hydrops in a multigravida with no medical history of note. She presented in her current pregnancy with a significant history of having 4 (out of 7) previous pregnancies affected by hydrops. Treatment: All the affected pregnancies resulted in mid-trimester pregnancy termination (MTPT) following diagnosis in the second trimester. Previous investigations for hydrops did not yield any obvious cause. Outcome: Her most recent pregnancy was unaffected. We discuss the possible differential diagnoses and the likelihood of autosomal recessive metabolic diseases being the aetiological factor. Conclusion: Rare causes of fetal hydrops need to be excluded in cases of recurrent non-immune hydrops with no obvious aetiology following routine investigations. Key words: Hydrops fetalis, Lysosomal storage disorders, Non-immune, Thalassaemia, Ultrasonography
Raised CA 125 levels have been shown to be associated with various etiologies, notably ovarian cancer and endometriosis. We report a case of adenomyosis in a 53 year-old woman who presented with menorrhagia. The uterus was enlarged and she had a preoperative CA 125 level of > 6000 IU/ml. A total abdominal hysterectomy and bilateral salpingoophorectomies was done with an intraoperative frozen section. It showed adenomyosis and paraffin sections of the specimen confirmed no malignancy. The extremely elevated CA 125 level returned to the normal range postoperatively.
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