Adenomyosis With Extremely Elevated CA 125 Levels

Abstract

Raised CA 125 levels have been shown to be associated with various etiologies, notably ovarian cancer and endometriosis. We report a case of adenomyosis in a 53 year-old woman who presented with menorrhagia. The uterus was enlarged and she had a preoperative CA 125 level of > 6000 IU/ml. A total abdominal hysterectomy and bilateral salpingoophorectomies was done with an intraoperative frozen section. It showed adenomyosis and paraffin sections of the specimen confirmed no malignancy. The extremely elevated CA 125 level returned to the normal range postoperatively.