Dielectrophoresis (DEP) is a very popular technique for microfluidic bio-particle manipulation. For the design of a DEP-based microfluidic device, simulation of the particle trajectory within the microchannel network is crucial. There are basically two approaches: (i) point-particle approach and (ii) finite-sized particle approach. In this study, many aspects of both approaches are discussed for the simulation of direct current DEP, alternating current DEP, and traveling-wave DEP applications. Point-particle approach is implemented using Lagrangian tracking method, and finite-sized particle is implemented using boundary element method. The comparison of the point-particle approach and finite-sized particle approach is presented for different DEP applications. Moreover, the effect of particle-particle interaction is explored by simulating the motion of closely packed multiple particles for the same applications, and anomalous-DEP, which is a result of particle-wall interaction at the close vicinity of electrode surface, is illustrated.
Electro-kinetic manipulation Janus particles and droplets has attracted attention in recent years due to their potential application in microfluidics. Due to the presence of two different zone on the surface of particles with different charge distribution, the motion of the Janus particles are quite different than the that of regular particles. Therefore; the fundamental understanding of this motion is the key element for the further development of the microfluidic systems with Janus particles. In present study, electro-kinetic motion of Janus droplets inside a micro-channel is modeled using boundary element formulation. 2D formulation is verified against the reported experimental data in the literature. Results show that the 2D boundary element formulation is successful for the prediction of the electrophoretic velocity of the Janus droplets. The current formulation has a potential to model non-spherical particles and to study particle-particle and particle-wall interactions.
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