Although there are several studies regarding the association between RDW and the vascular events, information is scant about possible role of RDW in cardiovascular system. We aimed to investigate whether RDW is related with the severity and extent of angiographically assessed coronary artery disease (CAD

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E ect of overweight and obesity on the le ventricular systolic and diastolic functions in patients with acute myocardial infarction AbstractPurpose: e purpose of this study was to evaluate whether a association exits among overweight and obesity and le ventricular systolic and diastolic functions in patients admitted with rst ST-elevation myocardial infarction (STEMI).Methods: e present study was performed on 451 consecutive patients diagnosed with rst STEMI (376 men, 75 women; mean age 56.1±10.8 years). e patients were classi ed into three groups based on their body mass index (BMI) as normal weight (BMI < 25 kg/ m2), overweight (BMI: 25-29.9 kg/m2) and obese (BMI>30 kg/m2). Echocardiographic features were evaluated and compared among the three groups.Results: Mitral annulus E velocities were higher in obese individuals than normal weight group (p <0.01). In contrast, mitral A velocities were lower (p =0.03); consequently, E\A and E'\A' ratios were lower (both p =0.01) in the obese group with respect to normal weight group. When the correction of entire variations existing among the groups were performed using multivariate linear regressions analyses, it turned out that BMI was independently associated with E/A (β= -0.19, p =0.044) and with E'/A' (β= -0.016, p=0.021). Ejection fraction, wall motion score index and myocardial S velocities were comparable among the study groups (p >0.05).Conclusion: ese results suggest that while obesity has no adverse e ect on the le ventricular systolic function, it has unfavorable consequences on the le ventricular diastolic function in the patients with rst STEMI. In contrast, no unfavorable e ects of overweight on the le ventricular systolic and diastolic function were detected.