In addition to the larger amount of trefoil, coma, tetrafoil, and secondary astigmatism, keratoconic eyes tend to have a reverse coma pattern and reverse trefoil aberrations compared with normal eyes. Although RGP lenses correct the irregular astigmatism, smaller comet-like retinal images in the opposite direction remain due to residual vertical coma.

Corneal HOAs on both corneal surfaces in keratoconic eyes were higher than in control eyes. Coma from the posterior surface compensated partly for that from the anterior surface. Residual irregular astigmatism in patients with keratoconus wearing rigid gas permeable contact lenses can be estimated by measuring the HOA from the posterior corneal surface.

ABSTRACT.Purpose: To identify localization and kinetics of infiltrated cells and cytokines in murine herpetic keratitis. Methods: HSV-1 was inoculated onto the scarified BALB/c corneas. At given times post infection (PI), eyes were removed and studied immunohistochemically using monoclonal antibodies against several infiltrated cells and cytokines.

Although PMCD and KC are categorized as noninflammatory corneal thinning disorders, the HOA patterns in the 2 groups differed, possibly due to differences in the positions of the corneal apex. PMCD and KC may cause distinctively different deterioration in the quality of vision.

This series of cases presented a unique type of idiopathic endotheliitis with the clinical appearance of multiple and parallel lines of keratic precipitates. The expression patterns of the keratic precipitates were distinct from those of previously reported linear endotheliitis.

Although flap creation and laser ablation were supposed to center on the primary line of sight in LASIK, keratectasia after LASIK showed coma-dominant HOAs at both corneal surfaces. This suggests that the cornea in keratectasia has optical properties similar to those in keratoconus.

The OATz profile may decrease the surgically induced increase of higher order aberrations, especially spherical aberration, following LASIK. However, a study with equivalent treatment groups and larger sample sizes is required for a definitive conclusion.

This is the first report of the corneal infiltration seen in an AIDS patient with CMV retinitis. Etiological significance of the finding is discussed.