We investigated the possibility to grow molecularly porous amino-silane layers on glass-like substrates. The goal of this work is to show that it is possible to substantially increase the sensitivity of a fluorescence sensor by adjusting the functionalization strategy. Two methods are studied, one using APTMS only and another one using both APTMS and APDMS. We show that, using the second method, sensor sensitivity is improved by a factor of about 5. In order to demonstrate this, we applied the technique to the grafting of fluorescein in order to build a fluorescence pH sensor.
The goal of this work concerns a new method to substantially increase the sensitivity of a fluorescence pH sensor. The method is based on a double silanization method. Two methods are compared: one using APTMS (3-Aminopropyl)trimethoxysilane) only and another one using both APTMS and APDMS (3-Aminopropyl)dimethoxymethylsilane). Using the second method, sensor's sensitivity is improved by more than 500 %.
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