Background: Adrenal haemorrhage (AH) in the new-born is not that uncommon and has been reported frequently. AH occurs most often after a traumatic delivery or complicated neonatal course. Design and setting: A retrospective, hospital-based study conducted at king Khalid university hospital (KKUH), endocrine service, Riyadh, Saudi Arabia, during the period January 2014 and July 2018. Methods: Medical records of neonates who had been diagnosed to have AH were reviewed. Data included age, sex, clinical manifestations, laboratory and radiological investigations. Results: During the period under review, five neonates were diagnosed to have adrenal haemorrhage. All were term male infants, who were delivered vaginally .one baby was large for gestational age (LGA), and three babies had perinatal hypoxemia. Clinical symptoms were not specific and diagnosis was confirmed by performing abdominal sonography (USG). Conclusion: AH should be recognised in the new-borns with nonspecific symptoms who had potential risk factors. Abdominal ultrasonography (USG) should be performed to diagnose AH, and monitor its progress. Adrenal hormone testing also should be performed.
Background: Congenital hypopituitarism is a clinical syndrome of deficiency in pituitary hormones production. Panhypopituitarism refers to involvement of more than one pituitary hormone while involvement of one hormone refers to partial hypopituitarism It is an uncommon disorder of the hypophyseal system but could be life threatening, however, it is treatable if the diagnosis is made early.
Osteoporosis is recognized as an adult metabolic bone disease, and constitutes a major public health problem world-wide. It is, currently, emerging as a newly recognized problem in children and adolescent. Increased awareness and availability of Dual-Energy X-Ray Absorptiometry (DEXA) facilitate diagnosis. Paediatricians should be familiar with all aspects of the disease and contribute to its prevention and management.In this brief review, childhood osteoporosis is presented to highlight its pathogenesis, diagnosis and management.
This article describes a 14-year-old-female who presented initially with short stature and phenotypic features of turner's syndrome, which was confirmed later by Karyotype to have mosaic 45XO/47XXX. She had delayed puberty and proved (hormonally) to have ovarian failure, with absent Mullerian structures (radiologically).
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