The streamline flat steel box girder is broadly used in long span cable-supported bridges all over the world. As one of the most important part of the bridges, its stress level and distribution under various dynamic loads are especially concerned. However, it is difficult to obtain the accurate stress of the steel box girder by common finite element (FE) calculation. The Runyang Suspension Bridge (RSB) is taken as an example. To increase the accuracy of results, a 3-dimensional FE full model for the RSB is created by ANSYS and a spatial submodel of the steel box girder is particularly built with greater detail. Submodeling method is then employed as a connection technique to link different scale models. After the global analysis and connecting process, the local stress of the steel box girder under various vehicle loads is obtained by submodel analysis. The composite action between the full model and the submodel is analyzed, and the reasonable mesh size for the submodel is specially investigated. The numerical results are proved to be accurate by the field test results. This study demonstrates the reliability and efficiency of the submodeling method; and can provide references for accurately analyzing and designing the steel box girders of other long span bridges.
Apolipoprotein E type 4 allele (ApoE∊4) is known as a risk gene for the late-onset Alzheimer's disease, and the relationship between ApoE∊4 and cognitive function of the elderly people has drawn the attention of the scientists. In this study, we investigated the relationship between ApoE∊4 and the cognitive function of the old people. A total of 156 old people were investigated, of whom 31 were ApoE∊4 carriers. The ApoE∊4 primarily influenced the global cognitive function, perceptual speed, and work memory. The results indicate that ApoE∊4 has significant negative effect on the cognitive function of the elderly people who are 60 years and older.
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