Purpose
– The purpose of this paper is to examine how home institutions moderate the influence of internationalization, and the effect this has on the performance of stock-listed Chinese firms.
Design/methodology/approach
– A sample of 118 stock-listed Chinese firms over the period 2006-2011 was considered, using the panel data method.
Findings
– The results show that foreign ownership and region-specific marketization help firms reap the performance benefits of internationalization, while state ownership plays an insignificant role.
Research limitations/implications
– The findings may not hold for unlisted firms, service firms or firms from other emerging economies.
Practical implications
– The study suggests that Chinese managers should take advantage of home country institutions to improve the effects of internationalization on performance.
Originality/value
– This research suggests that the analysis of the performance consequences of internationalization should go beyond the nexus between internationalization and performance, and also consider the home institutional factors that may facilitate or constrain the focal relationship.
The aim of the present study was to evaluate the effects of programmed cell death 4 (PDCD4) on cell proliferation and apoptosis, and to elucidate the potential role of the Jun N-terminal kinase (JNK)/c-Jun pathway in human bladder cancer (BCa) cells. Mixed BCa cells were transfected with plasmids containing PDCD4 (PDCD4-pcDNA3). The sensitivity to cisplatin was analyzed using cell viability, invasion/migration, apoptosis, flow cytometry, wound healing and Transwell assays at different transfection times. Furthermore, epithelial-to-mesenchymal transition (EMT) markers were detected by immunofluorescence staining, and the protein expression of c-Jun, and phosphorylated Jun N-terminal kinase (p-JNK) and c-Jun (p-c-Jun, Ser-73) were also tested using western blotting. It was observed that BCa cell proliferation and invasion and tumor growth were significantly inhibited, whereas apoptosis was enhanced in PDCD4-transfected cells treated with cisplatin compared with controls. Moreover, the western blotting and immunofluorescence results demonstrated that PDCD4 upregulated the expression of epithelial cell markers, but downregulated the expression of mesenchymal cell markers. Furthermore, overexpression of PDCD4 reduced the protein levels of p-JNK and p-c-Jun. Taken together, the findings of the present study indicate that PDCD4 enhances the sensitivity of BCa cells to cisplatin, partially via regulation of the JNK/c-Jun pathway, and reverses EMT. In conclusion, the results of the present study suggested that PDCD4, a nuclear/cytoplasmic shuttling protein with multiple functions, plays an important role in the development and progression of human BCa.
The rise of China’s outward foreign direct investment (OFDI) in Africa has promoted the continent’s economic growth but generated controversy in the West. What drives Chinese investment in the continent with abundant natural resources but poor institutions/governance? While the topic is important, studies on the issue in the literature have been limited. This paper attempts to close the gap by testing hypotheses of the role of resources and institutions with panel data in 2003–2013. Estimates suggest that the Chinese investment is not biased toward resource-rich and institution-poor countries but similar to Western investment, and China’s OFDI is largely profit-driven, just like investors from other countries. Institutional supports from the Chinese government, however, seems to be important to China’s OFDI in Africa.
Dihydromyricetin is a natural food additives with good prospects in food industry, But its little research is on dihydromyricetin complex with better effects. Antibacterial agent is very important in food industry, but little attention has been devoted to the relationship between dihydromyricetin-metal complex and antibacterial activity. In this paper, dihydromyricetin-Co(II) has been prepared and the interaction of dihydromyricetin-Co(II) complx with antibacterial activity was investigated by tube double dilution method. The results indicate that the dihydromyricetin-Co(II) conditional stability constant is 6.47 × 10 13 L 2 mol -2 and its antibacterial activity could effectively inhibit the growth of Candida albicans. The minimum antimicrobial dosage of dihydromyricetin-Co(II) against Candida albicans was 12.5-25 µg/mL. The minimum bactericidal dosage was 25-50 µg/mL. The result showed dihydromyricetin-Co(II) against Candida albicans was stronger than that of dihydromyricetin.
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