Men with coronary artery disease have significantly lower levels of androgens than normal controls, challenging the preconception that physiologically high levels of androgens in men account for their increased relative risk for coronary artery disease.

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LGE, p<0.001). There was a strong positive correlation between T2 values in the BIFL wall and ln(hsTnT) (r=0.776, p<0.001, figure 2). The strongest predictor of increased hsTnT Abstract 1 Figure 1 Box-plot graph showing T2 values in remote and BIFL (LGE) areas Abstract 1 Figure 2 Scatter-plot graph illustrating a positive correlation between T2 values in the BIFL wall and blood hsTnT Abstract 1 Figure 3 Native T1, T2 and ECV mapping values measured in the septum and basal inferolateral wall. Typical BIFL wall scar is seen. Note the increased T2 mapping values matching the areas of LGE

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A positive family history is an established risk factor for ischaemic heart disease, but the size of the contribution relative to classical risks is open to debate. The literature suggests that inherited factors are important in the development of premature ischaemic heart disease, but decline in importance with age. A polymorphism in the angiotensin-converting-enzyme gene was the first new genetic factor thought to contribute independently and significantly to cardiovascular risk. However, more recent large prospective studies have indicated that its contribution is smaller than was originally thought. Interventions should continue to be targeted at the reduction of important environmental factors, such as smoking cigarettes.

MfSD "physiological hyperparathyroidism". Our data show the gravid IDD woman maintaining normal Ca and a normal response to Ca loading despite suppressed PTHi. The greater risk of hypocalcaemia in their infants implies the feto-placental unit may not compensate similarly. l6.6i5.7' 16.3i6.2' 12.2i3.9' 12.7L5.1' 14.635 4 M8 METABOLITES IN ITS PATHOGENESIS CP WILLIAMS [Introduced] and WH