Purpose: To describe the anesthetic protocol and the intubation technique without visualizing the trachea in rabbits, in order to enable the videolaparoscopic surgical procedure. Methods: The experiment was performed on 33 female rabbits (Oryctolagus cuniculus), aged from 5 to 7 months. It consisted of general anesthesia and endotracheal intubation by manual palpation of the trachea of the rabbits, without using the laryngoscope, orally, for later videolaparoscopic surgical access to the abdominal cavity. Results: The mean values and standard deviation of vital parameters of the animals were 223.8±15.61 beats per minute for heart rate; 35±9 movements per minute for respiratory rate; 96.94±0.99% of oxymetry and 42.82±4.02 mmHg for capnometry; 16.7±4.3 minutes for pneumoperitoneum (duration of surgery) and 1 hour and 14±8.52 minutes for time of observation (from induction to recovery from anesthesia). All animals were intubated in at most three attempts. No animals were lost after the introduction of this anesthetic technique. Conclusion: This protocol proved adequate, safe and easy to perform, on rabbits submitted to videolaparoscopic surgery. Key words: Anesthesia. Laparoscopy. Surgery. Animal Experimentation. Rabbits. RESUMO Objetivo:Descrever o protocolo anestésico e a técnica de intubação sem visualização da traqueia em coelhos, para viabilização de procedimento cirúrgico videolaparoscópico. Métodos: O experimento foi realizado em 33 coelhas (Oryctolagus cuniculus), com idade entre 5 e 7 meses. Consistiu de anestesia geral e intubação endotraqueal por meio de palpação manual da traquéia das coelhas, sem o uso de laringoscópio, pela via oral, para posterior acesso cirúrgico videolaparoscópico da cavidade abdominal. Resultados: Os valores médios e desvio padrão dos parâmetros vitais dos animais foram de 223,8±15,61 batimentos por minuto para freqüência cardíaca; 35±9 movimentos por minuto para frequência respiratória; 96,94±0,99% de oximetria e 42,82±4,02 mmHg para capnometria; 16,7±4,3 minutos para o pneumoperitônio (tempo de cirurgia) e 1 hora e 14±8,52 minutos para o tempo de observação (desde a indução até a recuperação anestésica). Todos os animais foram intubados em, no máximo, três tentativas. Não houve perda de animais após a introdução dessa técnica anestésica. Conclusão: Este protocolo mostrou-se adequado, seguro e de fácil realização, para a aplicação em coelhos submetidos à cirurgia videolaparoscópica.
No difference was found using barrier methods, Surgicel(®), and Interceed(®) for preventing adhesion formation in videolaparoscopy.
Purpose:To verify the frequency of postsurgical pelvic adhesion formation in an experimental animal model using videolaparoscopy. Methods: Experimental study in a sample of 11 non-pregnant female rabbits, aged 5 to 7 months. After general anesthesia, access to the abdominal cavity was performed by an open puncture technique, with 10mm optics, placing two other 5 mm trochars under direct visualization, in the iliac fossae. Then a fragment of peritoneum was resected, followed by electrocauterization. In 21 days, the videolaparoscopy was repeated, and adhesion formation and score was looked at, with biopsies at the surgical site. Results: 54 % of adhesion formation was observed, and the median score of adhesions was 6 (minimum of 3 and maximum of 10), all of them found in the bladder and the anterior abdominal wall. Conclusion: The method used presents a high frequency of intra-abdominal adhesion formation. Key words: Adhesions. Laparoscopy. Surgery. Rabbits. RESUMOObjetivo: Verificar a freqüência da formação de aderências pélvicas pós-cirúrgicas, em um modelo experimental animal, por videolaparoscopia. Métodos: Estudo experimental, em uma amostra de 11 coelhas, não prenhas, com idade entre cinco e sete meses. Após anestesia geral, o acesso da cavidade abdominal foi efetuado por técnica de punção aberta, com óptica de 10 mm, colocando-se outros dois trocateres de 5 mm, sob visão direta, nas fossas ilíacas. Realizou-se, então, ressecção de fragmento de peritônio, seguida de cauterização com eletrocautério. Em 21 dias, foi repetida a videolaparoscopia, verificando-se a formação e escore de aderências e realizando-se biópsias do local da cirurgia. Resultados: Observou-se 54,5% de formação de aderências, sendo o escore total mediano de aderências seis (mínimo de três e máximo de 10), todas encontradas na bexiga e na parede abdominal anterior. Conclusão: O procedimento utilizado apresentou alta freqüência de formação de aderências intra-abdominais. Descritores: Aderências. Laparoscopia. Cirurgia. Coelhos.
Splenic artery aneurysm is a rare condition with a prevalence of less than 1% in the general population and is more common in women; however, it is the third most common cause of intra-abdominal aneurysms and the most common among visceral arterial aneurysms 1 . This condition was first described by Beussier in 1770; some of the risk factors often described are: fibrodysplasia, portal hypertension, splenomegaly, cirrhosis of the liver, liver transplant, pancreatitis, vasculitis, infectious mononucleosis, and pregnancy [1][2][3][4][5][6] . Pregnancy is considered the most important risk factor for the rupture of this aneurysm, but the true prevalence of this event is unknown 2 . Increased splanchnic and splenic circulation during pregnancy has been indicated as one of the main factors in the development of aneurysms. The modifications in circulation induced by estrogen and progesterone during pregnancy may also contribute to weakening blood vessel walls, especially at the bifurcations. It is speculated that the greater the woman's parity the greater the risk of development and rupture of the aneurysm, due to the successive stresses to which the vessel wall is submitted 3 . The importance of an adequate diagnosis and management of this condition, despite its low prevalence, is supported by the high rates of maternal and fetal mortality, 75 and 95%, respectively 3 . CLINICAL CASEA 38-year-old pregnant woman with 41 weeks of gestational age and two previous vaginal deliveries without complications or known comorbidities was admitted to the obstetrical center of Hospital de Clínicas de Porto Alegre and treated according to a protocol for post-term pregnancy.At admission, the patient had a cervical dilation of 2 cm and weak uterine contractions, and cardiac-fetal heart rate was normal. After using intravenous oxytocin for 2 hours, in an infusion pump at a concentration of 10 mU/min, she presented a dynamic of three contractions in 10 min and was 5 cm dilated. Two hours later, during non-pharmacological approaches to relieve pain (bath in labor), she presented with strong abdominal pain, dyspnea, dizziness, and paleness. The medical team was called for assessment. At vaginal palpation amniorrhexis and complete cervical dilation were diagnosed, and the patient was sent to the delivery room in the expulsion stage.In the delivery room her dyspnea, respiratory effort, and hypotension became worse. She was submitted to orotracheal intubation and invasive measurement of arterial pressure by the anesthesia team, and volemic replacement was started. The delivery was performed with a left mediolateral episiotomy and fetal extraction with Simpson's forceps. A female baby was born weighing 3705 g and with Apgar scores of 2/6/9 in the 1st, 3rd and 5th minutes, respectively, and sent directly to the care of the Neonatal Unit. Umbilical cord blood gas showed a fetal pH of 6.9. Immediately after delivery, the rapid response team (RRT) was called and the patient was sent to the intensive care unit (ICU) on mechanical ventilation. A be...
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.