Standard-Nutzungsbedingungen:Die Dokumente auf EconStor dürfen zu eigenen wissenschaftlichen Zwecken und zum Privatgebrauch gespeichert und kopiert werden.Sie dürfen die Dokumente nicht für öffentliche oder kommerzielle Zwecke vervielfältigen, öffentlich ausstellen, öffentlich zugänglich machen, vertreiben oder anderweitig nutzen.Sofern die Verfasser die Dokumente unter Open-Content-Lizenzen (insbesondere CC-Lizenzen) zur Verfügung gestellt haben sollten, gelten abweichend von diesen Nutzungsbedingungen die in der dort genannten Lizenz gewährten Nutzungsrechte.
The influence of various variables on the rate of pneumothorax and intrapulmonal hemorrhage associated with computed tomography (CT)-guided transthoracic needle biopsy of the lung were evaluated retrospectively. One hundred and thirty-three patients underwent CT guided biopsy of a pulmonary lesion. Two patients were biopsied twice. Variables analyzed were lesion size, lesion location, number of pleural needle passes, lesion margin, length of intrapulmonal biopsy path and puncture time. Eighteen-gauge (18G) cutting needles (Trucut, Somatex, Teltow, Germany) were used for biopsy. Pneumothorax occurred in 23 of 135 biopsies (17%). Chest tube placement was required in three out of 23 cases of pneumothorax (2% of all biopsies). Pneumothorax rate was significantly higher when the lesions were located in the lung parenchyma compared with locations at the pleura or chest wall (P < 0.05), but all pneumothorax cases which required chest tube treatment occurred in lesions located less than 2 cm from the pleura. Longer puncture time led to an increase in pneumothorax rate (P < 0.05). Thirty-seven (27%) out of 135 biopsies showed perifocal hemorrhage. Intrapulmonal biopsy paths longer than 4 cm showed significantly higher numbers of perifocal hemorrhage and pneumothorax (P < 0.05). Significantly more hemorrhage occurred when the pleura was penetrated twice during the puncture (P < 0.05). Lesion size <4 cm is strongly correlated with higher occurrence of perifocal hemorrhage (P < 0.05). Lesion margination showed no significant effect on complication rate. CT-guided biopsy of smaller lesions correlates with a higher bleeding rate. Puncture time should be minimized to reduce pneumothorax rate. Passing the pleura twice significantly increases the risk of hemorrhage. Intrapulmonal biopsy paths longer than 4 cm showed significantly higher numbers of perifocal hemorrhage as well as pneumothorax.
Standard-Nutzungsbedingungen:Die Dokumente auf EconStor dürfen zu eigenen wissenschaftlichen Zwecken und zum Privatgebrauch gespeichert und kopiert werden.Sie dürfen die Dokumente nicht für öffentliche oder kommerzielle Zwecke vervielfältigen, öffentlich ausstellen, öffentlich zugänglich machen, vertreiben oder anderweitig nutzen.Sofern die Verfasser die Dokumente unter Open-Content-Lizenzen (insbesondere CC-Lizenzen) zur Verfügung gestellt haben sollten, gelten abweichend von diesen Nutzungsbedingungen die in der dort genannten Lizenz gewährten Nutzungsrechte. While most of the debate has focused on the effects of QE on the US economy, foreign policy-makers -in particular in emerging markets-argued that QE policies have created excessive global liquidity and caused an acceleration of capital flows to EMEs. In turn, this capital flow surge is widely blamed for appreciation pressures on EME currencies and a build-up of financial imbalances in EMEs. Terms of use: Documents in EconStor mayTo shed some light on this issue, the paper analyses the effects of the Federal Reserve's unconventional policies on the US and on 65 foreign financial markets. Importantly, the paper extends the existing literature by investigating the effects on both global asset prices and capital flows. For this purpose, we use a relatively novel database of daily portfolio flows into bond and equity mutual funds, taking primarily a US investor perspective. In this way, we can track capital injections into funds (portfolio flows) across countries.We analyze different types of US unconventional monetary policy measures (liquidity operations, purchases of MBS and of US Treasuries) in order to understand whether and why QE1 and QE2 have exerted different effects on US and foreign markets. In contrast with most of the literature on US QE, which has focused narrowly on announcement effects, we make a distinction between announcements of Fed interventions and the actual market operations.The results in the paper illustrate how US monetary policy since 2007 has contributed to portfolio reallocation as well as a re-pricing of risk in global financial markets. First, we find that Fed measures in the early phase of the crisis (QE1) were highly effective in boosting bond and equity prices, especially in the US, and led to US dollar appreciation. Conversely, QE2 boosted equity prices worldwide and led to US dollar depreciation. Yet Fed policies functioned in a pro-cyclical manner for capital flows to EMEs and in a counter-cyclical way for the US. QE1 triggered a portfolio rebalancing across countries out of emerging markets (EMEs) into the US, while QE2 triggered rebalancing in the opposite direction. This finding may be interpreted as lending support to the concerns expressed by policymakers in EMEs. The results suggest that there are indeed global spillovers and externalities from monetary policy decisions in advanced economies. However, the paper is mute on whether such externalities are overall positive or negative for other economies. The potentially...
MR imaging-guided LITT yields high local tumor control and survival rates in well-selected patients with limited liver metastases of colorectal carcinoma.
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