Background & objective: To see the relationship between preeclampsia and iron parameters (serum iron, serum ferritin and total iron binding capacity). Methods: The present case-control study was carried out in the Department of Obstetrics & Gynaecology, Dhaka Medical College Hospital (DMCH), Dhaka in collaboration with the Department of Biochemistry, BSMMU, Dhaka over a period of 1 year from July 2012 to June 2013 Pregnant women with preeclampsia admitted in the above-mentioned hospital were considered as case, while the pregnant women without preeclampsia were included as control. A total of 60 women-31 cases and 29 controls were purposively included in the study. The exposure variables were serum ferritin, serum iron and total iron binding capacity (TIBC), while the outcome variable was preeclampsia. The serum iron level > 100 μg/L was considered as hyperferritenemia. Result: Nearly two-thirds of the women were in their 2nd decades of life belonged to lower socioeconomic class. The body mass index was also fairly comparable between the groups with most women having normal BMI. No significant difference was observed between the groups with respect to obstetric variables as well. Level of haemoglobin and hematocrit were also identically distributed between groups. The result showed that a significantly higher proportion (35.5%) preeclamptic women had elevated serum ferritin (> 100 μg/L) as opposed to 10.3% of the control group (p = 0.021). The risk of developing raised serum ferritin in women with preeclampsia was estimated to be 4-fold (95% CI =1.2 – 19.4) higher than that in the normal pregnant women. Analyses also revealed that women with severe preeclampsia had a higher mean serum ferritin (207.3 ± 44.1 ng/ml) than the women with mild preeclampsia (41.7 ± 2.7) and an even higher level compared with the normal pregnant women (21.7 ± 1.4 μg/ml) (p = 0.001). Similar result was observed in serum iron with greater the severity, higher is the level of serum iron (p = 0.067). Conversely, the serum total iron binding capacity (TIBC) was decreased with severity of preeclampsia (p = 0.058). Conclusion: The study concluded that women with preeclamsia might be associated with higher serum ferritin, higher serum iron and lower serum TIBC although it is not known whether the rise in serum ferritin and serum iron precedes or contributes to the clinical manifestations of preeclampsia. Ibrahim Card Med J 2017; 7 (1&2): 64-69
Background & objective: Among the gynaecological cases admitted in tertiary care hospitals, abortion occupies the highest position. But detailed studies about the pattern of abortion admitted in the hospitals are limited. The present study was intended to find the proportion of abortion cases to total admitted cases and describe the types, clinical presentation and consequences of abortions. Methods: This study was carried out among a cross-section of abortion patients admitted in the Department of Obstetrics and Gynaecology, Dhaka Medical College Hospital. A total of 100 women admitted with a history of abortion between January and June, 2003 were consecutively included in the study. On admission, blood sample was sent for blood grouping & cross-matching and estimation of haemoglobin. Additional investigations like routine blood test, TC, DC, urine for R/E were done in septic abortion cases. High vaginal swab was collected from all cases but only in 5 patients, it was possible to carry out culture and sensitivity test. All cases were admitted and followed up to discharge for studying their consequences. Result: Majority (61%) of the patients was admitted in their third decade of life. The included cases were predominantly poor (68%), Muslim (97%) and urban residents (78%). Over half (54%) of the patients were illiterate. Sixty percent patients were multipara, 21% primipara and 19% nullipara. Two patients were unmarried. One-quarter had previous history of 1-4 abortions. Of the 100 cases of abortions, over three-quarters (77%) were of spontaneous abortions and 23% were of induced abortions. Two-thirds (66%) of the cases presented with incomplete abortions, which among others, included incomplete MR (13%). Septic abortion was 12%; of which 10% were induced and 2% spontaneous abortions, complicated to septic abortions. Missed abortion was 10%, inevitable 10% and threatened 6%. Out of 100 cases, 86% required operative intervention which included dilatation, evacuation and curettage (95.2%), subtotal hysterectomy, repair of perforation, hysterotomy and colpotomy. Two threatened abortions cases continued their pregnancy. One threatened abortion, five missed abortion, one septic abortion and six inevitable abortion cases spontaneously expelled their product of conceptus. Seventy-nine patients received whole blood transfusion to compensate for haemorrhage. Over 80% were discharged from the hospital within 5 days. Complications (except anaemia) of abortion were found in 49% cases. One case of septic abortion with endotoxic shock and severe anemia died of the disease. Conclusion: Complications of abortion are preventable if the patients are made aware about the grave consequences of abortion and appropriate health services are extended at field levels. Ibrahim Card Med J 2020; 10 (1&2): 66-73
This descriptive cross sectional study was carried out to determine the current status of Quality Assurance Scheme in undergraduate medical colleges of Bangladesh. This study was carried out in eight (four Government and four Non- Government) medical colleges in Bangladesh over a period from July 2015 to June 2016. The present study had an interview schedule with open question for college authority and another interview schedule with open question for head of department of medical college. Study revealed that 87.5% of college had Quality Assurance Scheme (QAS) in their college, 75% of college authority had regular meeting of academic coordination committee in their college, 50% of college had active Medical Education Unit in their college, 87.5% of college authority said positively on publication of journal in their college. In the present study researchers interviewed 53 heads of department with open question about distribution, collection of personal review form, submission with recommendation to the academic co-coordinator, and annual review meeting of faculty development. The researchers revealed from the interviews that there is total absence of this practice which is directed in national guidelines and tools for Quality Assurance Scheme (QAS) for medical colleges of Bangladesh. Bangladesh Journal of Medical Education Vol.13(1) January 2022: 33-39
Introduction: : Preterm birth as a consequence of preterm labour is the major clinical problem associated with perinatal mortality, serious neonatal morbidity and moderate to severe childhood disability and two-thirds of all perinatal deaths. Moreover, preterm labour comprises a large number of low birth weight babies. Global incidence of preterm labour is 5-10% of all births. The aim of this study was to determine the clinical profile and to find out pregnancy outcomes of preterm labour. Materials & Methods: This cross-sectional study was conducted in Sir Salimullah Medical College Mitford Hospital, Dhaka from January 2005 to December 2005. A total 103 gravid women who got admitted with established premature labour pain were included as study patients. Preterm labour associated with severe pre-eclampsia, eclampsia, antepartum haemorrhage and intrauterine fetal death were excluded. Data were collected in a pre-designed questionnaire and analyzed by SPSS software. Results: Incidence of preterm labour was found 6.3%. Among maternal morbidities, puerperal sepsis found to be highest (14.56%) followed by UTI (7.77%), PPH (6.80%), wound infection (5.83%) and retained placenta (3.88%). This study found perinatal mortality 32.0% and morbidity 49.5% of which RDS contributed highest (24.27%) followed by neonatal jaundice (11.65%), septicemia (8.73%), neonatal convulsion (2.91%) and umbilical sepsis (1.94%). Conclusion: Preterm labor followed by preterm birth significantly contributes to maternal morbidity and perinatal morbidity and mortality. Medicine Today 2021 Vol.33(2): 143-146
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