Abstract:Background & objective: Among the gynaecological cases admitted in tertiary care hospitals, abortion occupies the highest position. But detailed studies about the pattern of abortion admitted in the hospitals are limited. The present study was intended to find the proportion of abortion cases to total admitted cases and describe the types, clinical presentation and consequences of abortions.
Methods: This study was carried out among a cross-section of abortion patients admitted in the Department of O… Show more
“…According to The World Health Organization, miscarriage is defined as the expulsion or extraction of a fetus (embryo) weighing less than 500 gm or before 24 weeks gestation (1,2) , it could be early pregnancy loss when happens before 12 weeks gestation or late pregnancy loss when it happened between 12 and 24 weeks gestation (2) . According to the guidelines of the European Society for Human Reproduction and Embryology and the Royal College of Obstetricians and Gynecologists, recurrent spontaneous miscarriage is often characterized by a sequence of three or more consecutive miscarriages.…”
Accumulating evidence suggests that Wnt/β-catenin pathways play an important role in the physiological processes of endometrial development and differentiation, preimplantation embryo development, and blastocyst implantation. The objective of the current study was to signify the association between Wnt/β-catenin signalling pathway and recurrent spontaneous miscarriage and examine the expression of β-catenin first-trimester villi and decidua in women with spontaneous miscarriage. A comparative cross-sectional study was conducted in Saladin General Hospital from the 1st of January to the 1st of October 2021. A convenient sample of 80 pregnant women was enrolled in the current study and consisted of group A (40 pregnant women who were presented with first or second miscarriage) and group B (40 pregnant women who were presented with recurrent spontaneous miscarriage). There was a significant association between decreased β-catenin and recurrent miscarriage as 77.5% of the women who presented with recurrent spontaneous miscarriage had decreased levels of β-catenin, while only 32.5% of those with first or second miscarriage had decreased levels of β-catenin. The results of the current study implied that β-catenin is a valuable biomarker for unexplained recurrent spontaneous miscarriage. The women who presented with recurrent spontaneous miscarriage had a decreased expression of β-catenin .
“…According to The World Health Organization, miscarriage is defined as the expulsion or extraction of a fetus (embryo) weighing less than 500 gm or before 24 weeks gestation (1,2) , it could be early pregnancy loss when happens before 12 weeks gestation or late pregnancy loss when it happened between 12 and 24 weeks gestation (2) . According to the guidelines of the European Society for Human Reproduction and Embryology and the Royal College of Obstetricians and Gynecologists, recurrent spontaneous miscarriage is often characterized by a sequence of three or more consecutive miscarriages.…”
Accumulating evidence suggests that Wnt/β-catenin pathways play an important role in the physiological processes of endometrial development and differentiation, preimplantation embryo development, and blastocyst implantation. The objective of the current study was to signify the association between Wnt/β-catenin signalling pathway and recurrent spontaneous miscarriage and examine the expression of β-catenin first-trimester villi and decidua in women with spontaneous miscarriage. A comparative cross-sectional study was conducted in Saladin General Hospital from the 1st of January to the 1st of October 2021. A convenient sample of 80 pregnant women was enrolled in the current study and consisted of group A (40 pregnant women who were presented with first or second miscarriage) and group B (40 pregnant women who were presented with recurrent spontaneous miscarriage). There was a significant association between decreased β-catenin and recurrent miscarriage as 77.5% of the women who presented with recurrent spontaneous miscarriage had decreased levels of β-catenin, while only 32.5% of those with first or second miscarriage had decreased levels of β-catenin. The results of the current study implied that β-catenin is a valuable biomarker for unexplained recurrent spontaneous miscarriage. The women who presented with recurrent spontaneous miscarriage had a decreased expression of β-catenin .
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.