Levodopa (LD) determination was achieved for the first time by a cooper metal‐organic framework (MOF) based nanocomposite modified electrode. This research describes a simple, sensitive and cost‐effective electrochemical method for the detection of LD in real samples and the laboratory samples. This method is based on LD oxidation on glassy carbon electrode (GCE) surface modified with multi‐walled carbon nanotubes and copper terephthalic acid MOF (MWCNTs/Cu (TPA) MOF) nanocomposite. MOF was synthesized by the hydrothermal method. The synthesized MOF was characterized by Fourier‐transform infrared spectrophotometry (FT‐IR), energy‐dispersive X‐ray spectroscopy (EDX), field emission scanning electron microscopy (FESEM) and X‐ray diffraction (XRD). Electrochemical studies were accomplished by square wave voltammetry (SWV) and cyclic voltammetry (CV). The applied MOF, as a Cu‐containing synthetic peroxidase enzyme, can electrocatalyze oxidation of LD on the electrode surface and in incorporation with MWCNTs illustrated satisfactory synergic electrocatalytical properties which leads to sensitive detection of LD in the human serum sample. Limit of detection (LOD), sensitivity and linear range were 2 nmol L–1, 2.26 μA/μmol L–1 and 0.9‐35 μmol L–1 respectively, which in compared to other enzymatic or non‐enzymatic sensors were completely satisfying. Ultimately, stability, repeatability and reproducibility of as‐prepared sensor were investigated and the results were acceptable.
MIL-53 (Fe) Metal-organic framework (MOF) was synthesized by a hydrothermal method and characterized by SEM, XRD, FT-IR, and Brunauer-Emmett-Teller techniques. The synthesized MOF was successfully applied as an efficient catalyst in Electro-Fenton degradation of linear alkylbenzene sulfonate (LAS) surfactant, so that degradation rate constant, K app, for LAS degradation showed significantly higher amounts in presence of Fe MOF. Effect of experimental parameters on Electro-Fenton degradation including pH, MOF amount, applied current, Fe (II) concentration, and electrodes distance were investigated and optimized amounts were found. Applying of MOF caused efficient removal of LAS in compared to when MOF was not applied. Catalytic electrochemical degradation in this work showed removal of more than 98 % of initial surfactant in 150 min which was completely satisfying for LAS removal.
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