High resolution microradiography and multiple fluorochrome labeling are definitive histological methods for assessing the mechanism and timing of osseous healing, maturation, and adaptation. Two fundamental types of bone interface have been described for endosseous dental implants: (1) fibro‐osseous integration (“pseudo‐periodontal ligament”) and (2) rigid osseous fixation (“osseointegration”). No definitive bone interface studies with modern physiological methods have been reported for fibro‐osseous integration. Rigid osseous fixation has been investigated in cortical bone implantation sites. The initial healing reaction involves predominantly bone modeling at the periosteal and endosteal surfaces, i.e., a woven bone callus fills with lamellae by the process of lamellar compaction. Nonvital osseous interface and adjacent compacta are replaced by bone remodeling (turnover). As assessed with high resolution microradiography, “clinically successful” specimens had less than half of the intraosseous interface in direct contact with bone. Extrapolation from animal data suggests that endosseous implants can be provisionally loaded at about 18 weeks, but full maturation of the interface requires approximately one year.
Outcomes of infants with isolated gastroschisis were not significantly affected by method or site of delivery, diagnostic method, or maternal-fetal surveillance. Although the findings of this investigation were largely negative and the statistical power limited due to the rarity of this fetal disruption, small series of cases of gastroschisis need to be analyzed to resolve current controversies surrounding optimal treatment of gastroschisis.
In this population of women receiving outpatient preterm-labor management services, 95.1% of excessive MUA or patient-reported symptoms of preterm labor were managed on an outpatient basis. Outpatient management allowed for appropriate identification and triage of women requiring hospital admission.
In this population of women receiving outpatient preterm-labor management services, 95.1% of excessive MUA or patient-reported symptoms of preterm labor were managed on an outpatient basis. Outpatient management allowed for appropriate identification and triage of women requiring hospital admission.
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