Fear of injection-related pain is a drawback to injectable therapy. Hypodermic injections are a cause for great anxiety and reduced adherence to the subcutaneous application of insulin for glycemic control in diabetics or in the treatment of multiple sclerosis, increasing the risk of complications and mortality. Injured or sick people have to undergo several daily injections, forcing them to rotate the veins and regions used to recover from the trauma caused by the perforation of the skin, tissue, muscles, veins, and arteries. People who suffer from type 1 diabetes mellitus (DM1) need to have their glycemic control 3 to 5 times a day and to take insulin up to 3 times a day. In both cases, the patient needs to perforate the skin. To quantify the pain perceived by the patients depends on the evaluation of each patient and therefore is subjective. This study aims to understand the application and self-application of hypodermic injections and decrease pain during its application and the phobia of the patient, following the reasoning that the lower the effort to penetrate the needle, the less trauma in the tissue and therefore the pain provoked. For that, it was analyzed how some of the characteristics of the needle can influence the sensation of pain in the injection. The needle penetration effort was measured in an artificial tissue (substitute skin model) for different cannula diameters, roughness, depth of penetration, lubrication, and angles of the perforating tip bevel. This study aimed to find alternatives to facilitate the application and self-application of hypodermic injections, increase safety and comfort, and reduce the pain intensity perceived by the patient. To do this, the bevel of needles used repeatedly was analyzed in the profile projector and SEM to verify the loss of the profile or the formation of burrs that could hamper the penetration or traumatize the tissue during the reuse of needles. It has also been mechanically analyzed, which can be done to prevent that the needles used in the subcutaneous application do not inadvertently reach the muscle. The greater penetration effort observed in the needles with greater angle of the bevel is responsible for the patient’s perception of pain.
Purpose In recent years, the mechanical industries began to apply many investments in research and technological development to obtain efficient methods to analyze the integrity of structures and prevent disasters and/or accidents, ensuring people’s lives and preventing economic losses. Any structure, whether mechanical or aeronautical, before being put into use undergoes a structural integrity assessment and testing. In this case, non-destructive evaluations are performed, aiming to estimate the degree of safety and reliability of the structure. For this, there are techniques traditionally used such as ultrasonic inspection, X-ray, acoustic emission tests, among other techniques. The traditional techniques may even have a good instrumental apparatus and be well formulated for structural integrity assessment; however, these techniques cannot meet growing industrial needs, even more so when structures are in motion. The purpose of this paper is to demonstrate artificial immune systems (AISs), ate and strengthen the emergence of an innovative technological tool, the biological immune systems and AISs, and these are presented as computing methods in the field of structural health monitoring (SHM). Design/methodology/approach The concept of SHM is based on a fault detection mechanism used in industries, and in other applications, involving the observation of a structure or a mechanical system. This observation occurs through the dynamic response of periodic measurements, later related to the statistical analysis, determining the integrity of the system. This study aims to develop a methodology that identifies and classifies a signal in normal signals or in faults, using an algorithm based on artificial immunological systems, being the negative selection algorithm, and later, this algorithm classifies the failures in probabilities of failure and degree of fault severity. The results demonstrate that the proposed SHM is efficient and robust for prognosis and failure detection. Findings The present study aims to develop different fast access methodologies for the prognosis and detection of failures, classifying and judging the types of failures based on AISs. The authors declare that the present study was neither published in any other vehicle of scientific information nor is under consideration for publication in another scientific journal, and that this paper strictly followed the ethical procedures of research and publication as requested. Originality/value This study is original by the fact that conventional structural integrity monitoring methods need improvements, which intelligent computing techniques can satisfy. Intelligent techniques are tools inspired by natural and/or biological processes and belong to the field of computational intelligence. They present good results in problems of pattern recognition and diagnosis and thus can be adapted to solve problems of monitoring and identifying structural failures in mechanical and aeronautical engineering. Thus, the proposal of this study demonstrates and strengthens the emergence of an innovative technological tool, the biological immune system and the AIS, and these are presented as computation methods in the field of SHM in rotating systems – a topic not yet addressed in the literature.
The purpose of this research is to analyze the phenomena connected to a shaft supported by two roller bearings using the concept and theory of Jeffcott rotors, whose dynamic behavior at a given speed, can represent phenomena such as displacement side of the shaft, misalignment of the shaft and to bearing failure, among others. The studies are conducted comparing the accelerations of the theoretical model to the experimental model, whose physical model has a one degree of freedom SDOF.
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