The influence of oral infections, especially periodontal disease, on systemic diseases has been extensively discussed in the literature. Because periodontal disease is a persistent infection, it promotes an inflammatory response. C-reactive protein is a marker for inflammatory reactions that is frequently studied, since elevated levels of this protein are related to coronary events.ObjectiveThe aim of this study was to investigate the effect of periodontal therapy on reducing the serum levels of C-reactive protein, by means of a systematic review of the literature and meta-analysis.Material and MethodsA systematic review of the English-language literature was conducted in the PUBMED-MEDLINE database, using the key words "periodontal disease", "C-reactive protein", "periodontal therapy" and "periodontal treatment", in accordance with the terms for Medical Subject Headings (MeSH), to evaluate the effect of periodontal therapy on C-reactive protein levels. A qualitative analysis of studies of randomized clinical trial design was performed using CONSORT, with subsequent meta-analysis.ResultsThe literature search initially retrieved 46 potentially relevant studies available in the databases. From these, in accordance with the inclusion criteria, only 11 were selected, of which only 4 fulfilled the criteria of randomized clinical trial design. According to CONSORT, the studies evaluated generally presented good quality with regard to the criteria analyzed. Through meta-analysis, the reduction in mean levels of C-reactive protein (-0.231; p=0.000) after introducing periodontal treatment was estimated. The result was statistically significant, without evidence of heterogeneity between the studies (p=0.311).ConclusionsThe findings indicated that non-surgical periodontal treatment had a positive effect with regard to reduction of the serum levels of C-reactive protein.
O fumo é um forte indicador de risco para implantes osseointegrados e os insucessos estão relacionados com as fases envolvidas durante o processo de reparo e Osseointegração, além da sobrevida dos implantes em decorrência do aumento da incidência de peri-implantite e mucosite peri-implantar, e como consequência em alguns casos a perda do implante. A nicotina representa a substância de maior expressão e toxicidade nos cigarros sobre os tecidos da cavidade oral. Assim, o presente estudo tem por objetivo revisar a literatura associando a influência e o risco do tabagismo à importância da saúde peri-implantar para previsibilidade do tratamento. Há estudos que também concluíram que o fumo aumenta o risco de peri-implantite e perda óssea peri-implantar. Assim, podemos concluir que o tabaco influencia negativamente na osseointegração e sobrevida dos implantes de titânio, devido aos efeitos citotóxicos das suas substâncias
Pênfigo é a denominação geral de um grupo de doenças autoimunes raras que acometem pele e mucosas e apresenta-se com formação de bolhas intraepidérmicas. O Pênfigo Vulgar (PV) é uma doença vésico-bolhosa crônica, rara, de natureza autoimune, quando não diagnosticada e tratada na sua fase inicial apresenta prognóstico grave. Este trabalho tem como objetivo relatar um caso clínico de uma paciente do gênero feminino, 32 anos de idade que apresentava manifestação de Pênfigo Vulgar. Asmanifestações bucais são, em sua maioria, os primeiros sinais da doença e o cirurgião-dentista possui papel fundamental no diagnóstico precoce.
Purpose: C-reactive protein (CRP) is a marker of inflammation that is naturally present in the plasma at levels that may rise due to inflammatory processes, associated with a greater risk of cardiovascular events such as acute myocardial infarction. Periodontal disease is responsible for a host immune-inflammatory response, contributing towards clarifying its association with cardiovascular disease. The aim of this study was to investigate the effect of periodontal therapy on the levels of this inflammatory marker. Methods: The sample consisted of 62 patients of both genders, between the ages of 30 to 60 years, who were referred to dental treatment at the Bahia Foundation for the Development of Sciences, and they were divided into two groups: with and without periodontitis. The clinical descriptors used were the bleeding index, gingival recession, probing depth and clinical attachment level. For CRP analysis, peripheral blood was collected from these individuals and sent to a single clinical analysis laboratory. Results: The group with periodontitis was treated and the results showed that there was a statistically significant difference between the CRP levels before and after periodontal treatment (P<0.05). Conclusion: From the final findings, it may be concluded that non-surgical periodontal therapy showed a tendency to reduce the CRP serum levels.
With the population aging, the chronic diseases related to the seniors, as the osteoporosis, increased generating a problem of public health that affects the quality of life of the population directly. The osteoporosis is a systemic disease that causes the mineral unbalance of the bones causing bone fragility and increase in the probability of fractures. Besides the long bones, it can attack the alveolar processes of the jawbone and of the jaw, could worsen the disease periodontal and to take to the dental loss. The objective of this work is to approach, through a revision of the literature, the present knowledge about the possible influence of the osteoporosis in the periodontal disease and in the levels of the alveolar bone mineral density.
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