Extramedullary plasmacytoma is a rare disease, characterized histopathologically by infiltration of plasma cells of different maturities and producing monoclonal immunoglobulin outside the bone marrow. J.R.G., 52 years old, male, sought medical assistance due to amaurosis and blocked eye movements. We performed Magnetic Nuclear Resonance of the skull that showed discrete intermediate signal tissue, next to the optic nerve canal and homolateral superior orbital fissure, with slight extension to the lower orbital fissure, associated with thickening of the corresponding meninges, involving the proximal portion of the optic nerve, measuring 1.3 x 1.1 x 2.5 cm. Non-specific aspect, but suggestive of lymphoproliferative lesion. Right and extraorbital tumor excision was performed, in which it was not possible to completely resect the tumor. The anatomopathological examination of the piece showed a neoplasm of plasma cells (plasmacytoma). The diagnosis is made from the exclusion of Multiple Myeloma. The treatments of choice are radiotherapy, due to the high radiosensitivity in 80–100% of cases, and surgery for localized lesions.
Introduction:Schwannomatosis is a rare type of neurofibromatosis, usually affects people between ages 25 and 30 years old. Schwannomatosis causes tumors to develop on the cranial, spinal, and peripheral nerves. The most common symptoms are: chronic pain, which can occur anywhere in the body and can be disabling, numbness or weakness in various parts of the body, and muscle paresis. Two genes are known to cause schwannomatosis. Mutations of the genes SMARCB1 and LZTR1, which suppress tumors, are associated with this type of neurofibromatosis. We report the case of a patient victimized by schwannomas in the pelvic region and, as a consequence, neuromuscular injuries.Case Report: Patient under investigation of lesions in the lumbosacral plexus and clinical picture marked by pain in the iliopsoas muscle in the left pelvic region and ipsilateral involvement of the obturator nerve (mild paresis in the adduction of the thigh and allodynia in the anterolateral region). A positron emission tomography-
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.