Intake of milk by fasted rats was reduced 50% below normal after their blood had been transfused with that of satiated rats. Bar pressing continuously reinforced by dry-food pellets was reduced to approximately 60% of normal following similar transfusion. Milk intake and bar pressing was not reduced when transfusion was between a pair of fasted rats. Bar pressing reinforced on a variable interval schedule was unaffected by transfusion between fasted-trained rats and satiated rats. In no case was food intake by satiated rats elevated following transfusion with fasted rats.
Intake of food by hungry rats was reduced 50 percent below normal after their blood had been mixed with that of satiated rats. Intake of food by deprived rats was not reduced when the donor rat was deprived of food for 24 hours prior to mixing of the blood or when a deprived donor was fed to satiety immediately before such transfusion.
An unusual case of carcinoma of the prostate with metastases is described. the prostate and the metastases showed adenocarcinoma with carcinoid-like areas. A tumor with the same histologic features was found at the tip of the appendix and proved to be metastatic. The possibility of primary carcinoid of the prostate was considered; however, Fontana-Masson stain and electron microscopy failed to confirm this. Immunoperoxidase stain for prostatic acid phosphatase was done on the prostate and metastases. This stain is specific for tissues of prostatic origin. The stain was positive in the carcinoid-like areas, indicating that it was not a true carcinoid but rather prostatic carcinoma with a carcinoid-like pattern. Apparently, this is the first case of a metastatic prostatic carcinoma showing carcinoid-like areas that were positive for prostatic acid phosphatase.
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