proceed in the forward direction from a specific starting compound to a target molecule.2 Streitwieser and Heathcock have included this analytical approach ill the chapter on organic synthesis in their text (6). They emphasize construction of the proper carbon skeleton, placement of functional groups, and control of stereochemistry.3 Pine, Hendrickson, Cram, and Hammond have treated this subject in the chapter on organic synthesis in their text (7). They distinguish between "construction" reactions and "functional alteration" reactions.
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