1980
DOI: 10.1021/ed057p868
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Computer-assisted teaching of organic synthesis

Abstract: proceed in the forward direction from a specific starting compound to a target molecule.2 Streitwieser and Heathcock have included this analytical approach ill the chapter on organic synthesis in their text (6). They emphasize construction of the proper carbon skeleton, placement of functional groups, and control of stereochemistry.3 Pine, Hendrickson, Cram, and Hammond have treated this subject in the chapter on organic synthesis in their text (7). They distinguish between "construction" reactions and "functi… Show more

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Cited by 12 publications
(8 citation statements)
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References 5 publications
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“…Make statistics for the word length distribution situation in corpus with word length distribution function, which is with important reference value for judging the difficulty of corpus text and language style [21][22][23][24].…”
Section: 2mentioning
confidence: 99%
“…Make statistics for the word length distribution situation in corpus with word length distribution function, which is with important reference value for judging the difficulty of corpus text and language style [21][22][23][24].…”
Section: 2mentioning
confidence: 99%
“…24 A teaching version of LHASA was developed, where the original set of 60 reagents known to the program was expanded to 138. 25 2) Deep searching and the combinatorial explosion. A retrosynthetic pathway may contain one or two particularly simplifying transforms-masterstroke disconnections that are the backbone of the strategy.…”
Section: Lhasamentioning
confidence: 99%
“…Several major mainframe programs for molecular orbital calculations and molecular modelling have been translated to IBM PC and are available from SERAPHIM and/or Quantum Chemistry Program Exchange. These can easily be incorporated into more advanced portions of the organic curriculum, as can computer-aided synthesis (29), though this still requires mainframe or minicomputer speed and power.…”
Section: Organic Chemistrymentioning
confidence: 99%