An assay of water content and specific gravity in normal and pathological autopsy brain has been correlated with CCT attenuation values obtained just prior to brain cutting. Formalin fixation does not alter normal values so that fixed brain appears to be suitable for this type of study. Low attenuation values in CCT correlate better with changes in specific gravity, rather than water in infarcts, but they have a close relationship to water content in edema. The high water content in infarcts of the white matter reveals a striking disparity in fluid control between cortex and white matter, which has not been emphasized in experimental studies. Water movement within and around blood clots has been discussed.
Before Shackleton arrived at South Georgia aboard Endurance on 5 November 1914 he was aware that the vessel might meet bad pack-ice in the Weddell Sea. This had been forecast on the basis of climate analysis by Robert Mossman, the meteorologist on the Scottish National Antarctic Expedition (1902–1904), who was currently working at the Argentine Meteorological Office. Mossman was interested in teleconnections linking meteorological and oceanic conditions in widely separated places and had studied the links between the Weddell Sea and South America. Mossman's Antarctic data were mainly records from the Orcadas station in the South Orkneys which had operated continuously from 1903. He found a correlation between extensive pack-ice in the Weddell Sea and plentiful rain in a belt across South America that included Buenos Aires. The experiences of Endurance supported this. Modern studies of the El Niño-Southern Oscillation (ENSO) broadly confirm Mossman's conclusions.
The construction and history of meridian transit beacons erected by members of the Imperial Trans-Antarctic Expedition at King Edward Cove, South Georgia, in 1914 are described.
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