Recent research suggests that psychedelic drugs can be powerful agents of change when utilized in conjunction with psychotherapy. Methylenedioxymethamphetamine (MDMA)-assisted psychotherapy has been studied as a means of helping people overcome posttraumatic stress disorder, believed to work by reducing fear of traumatic memories and increasing feelings of trust and compassion toward others, without inhibiting access to difficult emotions. However, research studies for psychedelic psychotherapies have largely excluded people of color, leaving important questions unaddressed for these populations. At the University of Connecticut, we participated as a study site in a MAPSsponsored, FDA-reviewed Phase 2 open-label multisite study, with a focus on providing culturally informed care to people of color. We discuss the development of a study site focused on the ethnic minority trauma experience, including assessment of racial trauma, design of informed consent documents to improve understanding and acceptability to people of color, diversification of the treatment team, ongoing training for team members, validation of participant experiences of racial oppression at a cultural and individual level, examination of the setting and music used during sessions for cultural congruence, training for the independent rater pool, community outreach, and institutional resistance. We also discuss next steps in ensuring that access to culturally informed care is prioritized as MDMA and other psychedelics move into late phase trials, including the importance of diverse sites and training focused on therapy providers of color.This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium for non-commercial purposes, provided the original author and source are credited, a link to the CC License is provided, and changesif anyare indicated.

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Chronic canaliculitis is an inflammation of the lacrimal canaliculus. Inflammation of lacrimal canaliculus can occur secondary to dacryocystitis, but the most common cause is infection. 1 Bacteria, fungi and viruses can cause infection. The most common presenting symptom of canaliculitis is chronic conjunctivitis. Actinomyces species is classically cited as the most common organism causing canaliculitis. 2-4 Concretions in the lower palpebral conjunctiva/fornix with conjuctivitis can also be the presenting symptom of Actinomyces infection. 5 We hereby report two cases of chronic conjunctivitis, one with canaliculitis and the other with palpebral concretions, both were positive for Actinomyces and responded to topical 5% cefazoline eyedrops. Case Report-1 A 50 year old male presented to us with complaints of chronic irritation,watering and occasional redness of the right eye since past 8 months. He was prescribed various topical antibiotic drops but he did not respond to any of them. On examination, his vision was 6/6 in both eyes. Examination of the right eye revealed a tender swelling in the medial one third of the right lower lid with congestion of adjacent lower palpebral conjunctiva and pouting lower punctum (Figure 1

Ophthalmomyiasis is the infestation of human eye with larvae of certain flies. Only a few cases of Ophthalmomyiasis externa have been reported from India. We report a human case of external ophthalmomyiasis caused by the larva of oestrus ovis (sheep botfly) for the first time, to the best of our knowledge, from Sonbhadra district of Uttar Pradesh. A 32 year old male patient presented with redness and watering in the right eye. A moving larva was found in his right inferior fornix and after its removal, the symptoms improved after a few hours.

The rapid advancement in fast pacing lifestyle of people and more dependent on fast food is the major leading cause of the increase in stomach infections leading to dysentery and diarrhea. Diarrhoea / Diarrhea and Dysentery are major causes of morbidity and mortality in rural communities of the developing world. The current review focus on herbal remedies from the Melghat region for dysentery and diarrhea-related symptoms. A total of 287 medicinal plant species from 90 families have been compiled for Dysentery (210) and Diarrhea (243). Most reported plant families were Fabaceae contributing 11.14% plants of the total population, followed by Asteraceae (5.57%), Malvaceae (4.52%), Apocynaceae (3.48%), Rubiaceae (3.48%), Lamiaceae (3.13%), Combretaceae (3.13%), Amaranthaceae (2.78%), Euphorbiaceae (2.78%), Moraceae (2.78%), Mimosoideae (2.43%), etc. In this study, out of 287 species reviewed, trees represented 34.49% of species, followed by herbs (32.75%), shrubs (21.95%), climbers (8.01%), grasses (2.43%), and orchids (0.34%). Curated data presented along with the plant's botanical name, plant's family, category (habit), ailments, the part used with relevant traditional, folk, ethnobotanical uses and patterns with cross citations offers scope for researchers engaged in herbal drug discovery and development to dwell into the herbal reservoir and find suitable plant compounds for fighting this disease.

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