Abstrak. Latar belakang : Penyakit kulit menyebabkan morbiditas yang tinggi, termasuk pada anak. Prevalensi dermatosis pada anak berkisar 34-87,7% dengan pola yang sangat bervariasi dan dipengaruhi oleh banyak faktor. Dampak penyakit kulit ini dapat mempengaruhi kualitas hidup anak.Metode : Penelitian retrospektif deskriptif  dengan  mengambil data dari rekam medis pasien anak dengan umur 1-18 tahun yang berobat ke Poliklinik Kulit dan Kelamin RSUP.Dr. M. Djamil Padang pada periode Januari 2016– Desember 2018. Hasil : Selama 3 tahun didapatkan 277 pasien baru, perempuan 123 (44,4%) dan laki - laki 154 (55,6%). Berdasarkan kelompok  penyakit yang terbanyak adalah dermatitis  (29, 9%), diikuti oleh infeksi jamur (16,9%), infestasi parasit (13, 4%),  infeksi virus (13, 3%), dan infeksi bakteri (6,9%).Kesimpulan:  Penyakit kulit terbanyak terjadi pada anak laki – laki. Infeksi jamur merupakan penyakit kulit paling sering, diikuti oleh infestasi parasit. Infeksi jamur yang sering terjadi adalah pitiriasis versikolor, sedangkan infestasi parasit yang paling sering adalah skabies.              Kata kunci: karakteristik penyakit kulit, anak, penelitian retrospektif Abstrack. Background: Skin disease causes high morbidity, including in children. The prevalence of dermatosis in children ranges from 34 to 87.7% with a pattern that is varied and influenced by many factors. The impact of this skin disease can affect the quality of life of childrenMethod : A descriptive retrospective, which is taking data from the medical records of patients aged 1 - 18 years who seek treatment at Dermatology and Venereology outpatient clinic at RSUP. M. Djamil Padang in the period January 2016 - December 2018.Result : During 3 years,there were 277 new patient which consist of 123 boy  (44.4%) and 154 girl (55.6%). Based on the group of diseases, dermatitis were the most common  disease (29,9%), followed by fungal infection (16.9%), parasit infestations (13,4%), viral infection (13,3%) and bacterial infection (6,9%). Conclusion : Most skin diseases occur in boys. Fungal infections were the most common skin diseases, followed by parasit infestations. The most common fungal infection is pityriasis versicolor, while the most frequent parasit infestation is scabies.Keywords:characterization of skin diseases, children, retrospective study

AbstrakSkabies adalah penyakit kulit akibat infestasi tungau Sarcoptes scabiei var hominis. Pada tahun 2014, penyakit kulit infeksi menduduki peringkat ketiga dari sepuluh penyakit terbanyak di puskesmas yaitu 1.926 kasus. Tujuan penelitian ini adalah menentukan faktor yang berhubungan dengan kejadian skabies di wilayah kerja puskesmas Lubuk Buaya Kota Padang tahun 2015. Penelitian ini bersifat analitik menggunakan desain case control dengan matching yang dilakukan di wilayah kerja Puskesmas Lubuk Buaya pada dari Januari sampai November 2015. Sampel kasus yaitu penderita skabies yaitu 31 orang diambil dengan total sampling. Sampel kontrol yaitu tidak menderita skabies sebanyak 31 orang dengan perbandingan 1:1. Data dianalisis secara univariat dan bivariat menggunakan ujiMc.Nemar. Hasil penelitian menunjukkan terdapat hubungan yang bermakna antar personal hygiene (p=0,022, OR=5), kepadatan hunian kamar (p=0,002, OR=4,5), luas ventilasi kamar (p=0,035, OR=3,67) dengan kejadian skabies sedangkan ketersediaan air bersih (p=0,454, OR=1,5) dan status gizi (p=0,23, OR=1,83) tidak memiliki hubungan yang bermakna dengan kejadian skabies. Tenaga kesehatan di puskesmas diharapakan dapat meningkatkan penyuluhan mengenai faktor-faktor yang mempengaruhi kejadian skabies. AbstractScabies is skin disease caused by infestation parasite Sarcoptes scabiei var hominis. In 2014, infection disease is on the third of ten the most common disease in puskesmas about 1.926 cases. The objective of this study was to determine risk factors that contribute on incidence of scabies in Puskesmas Lubuk Buaya Padang city 2015. This study is case control analytic design with matching. The study was conducted at Puskesmas Lubuk Buaya Padang from January to November 2015. The case sample were taken with total sampling comprised of 31 respondents suffering from scabies and the control comprised 31 respondents who were not suffering from scabies with comparison 1:1. The data were analyzed with univariate and bivariate analysis that is Mc Nemar test. The result of this study showed that there was a significant relationship between personal hygiene (p=0,022, OR=5,0), room density (p=0,002, OR=4,5), room ventilation (p=0,035, OR=3,67) with incidence of scabies, while availability of clean water (p=0,454, OR=1,5) and nutrition status (p=0,23, OR=1,83) not related with incidence of scabies. Health workers in puskesmas are expected to increase counseling about factors that affect incidence of scabies.

Vitiligo is an idiopathic disease characterized by depigmented patches on the skin due to loss of melanocytes. Vitiligo is often believed to be present in patients with vitamin B12 deficiency. Vitamin B12 are major determinants of homocysteine levels, and nutritional deficiency in these vitamins results in hyperhomocysteinemia. High levels of homocysteine are suspected to have toxic effects on melanocytes and cause vitiligo. This study aims to know the relation between serum homocysteine and vitamin B12 level with vitiligo severity. This work was an observational study with an analytic cross-sectional study design, consisting of 20 vitiligo patients aged 15-65 years who met inclusion and exclusion criteria. Vitiligo area severity index (VASI) score was calculated, and serum homocysteine and vitamin B12 levels were determined by ELISA method. The mean age of vitiligo patients in this study was 44.55 ± 14.36 years and mostly female (85%). The most common type is vitiligo Vulgaris (70%) with the degree of severity based on the VASI score has a mean of 20.33 ± 25.64. The mean serum homocysteine level was 10.33 ± 10.01 μmol / L and vitamin B12 level was 138.77 ± 156.07 pmol / L. The association between serum homocysteine and vitamin B12 with a VASI score was not statistically significant. There was no significant correlation between homocysteine levels and serum vitamin B12 with the severity of vitiligo. But in this study see the average vitamin B12 levels are lower than normal values.

Skabies adalah penyakit kulit akibat infestasi tungau Sarcoptes scabiei var hominis. Pada tahun 2014, penyakit kulit infeksi menduduki peringkat ketiga dari sepuluh penyakit terbanyak di puskesmas yaitu 1.926 kasus. Tujuan penelitian ini adalah menentukan faktor yang berhubungan dengan kejadian skabies di wilayah kerja puskesmas Lubuk Buaya Kota Padang tahun 2015. Penelitian ini bersifat analitik menggunakan desain case control dengan matching yang dilakukan di wilayah kerja Puskesmas Lubuk Buaya pada dari Januari sampai November 2015. Sampel kasus yaitu penderita skabies yaitu 31 orang diambil dengan total sampling. Sampel kontrol yaitu tidak menderita skabies sebanyak 31 orang dengan perbandingan 1:1. Data dianalisis secara univariat dan bivariat menggunakan uji Mc.Nemar. Hasil penelitian menunjukkan terdapat hubungan yang bermakna antar personal hygiene (p=0,022, OR=5), kepadatan hunian kamar (p=0,002, OR=4,5), luas ventilasi kamar (p=0,035, OR=3,67) dengan kejadian skabies sedangkan ketersediaan air bersih (p=0,454, OR=1,5) dan status gizi (p=0,23, OR=1,83) tidak memiliki hubungan yang bermakna dengan kejadian skabies. Tenaga kesehatan di puskesmas diharapakan dapat meningkatkan penyuluhan mengenai faktor-faktor yang mempengaruhi kejadian skabies.

Background: Seborrheic keratosis is a benign epidermal skin tumor caused by sun exposure, virus, and genetic factor. Human papillomavirus (HPV) infection presumed to have an important role in seborrheic keratosis. Protein p53 is a protein produced by tumor suppressor gene. There has been no research that correlates of HPV with p53 increase in seborrheic keratosis. Purpose: To prove the correlation between HPV and increased p53 expression in seborrheic keratosis. Methods: This study is an analytic cross-sectional comparative study. Samples were taken using a consecutive sampling method. There were 22 seborrheic keratosis patients recruited as the research sample. HPV were detected using the polymerase chain reaction (PCR), and p53 expression were detected using the immunohistochemistry examination. Result: The mean age of seborrheic keratosis patients in this study was 54.36±10.09 years, and they were predominantly males (54.5%). HPV were found in 86.4% of the seborrheic keratosis patients. The P53 expression (+) were 77.3%, (++) were 13.6%, and (+++) were 9.1%. All of the seborrheic keratosis with increased  p53 expression had positive HPV results, but with no significant results (p=0.600). Conclusion: There were no correlation between HPV with increased  p53 expression in seborrheic keratosis patients.

AbstrakSindrom Stevens Johnson (SSJ) merupakan reaksi mukokutaneus akut yang mengancam jiwa berupa nekrosis yang ekstensif dan lepasnya epidermis. Sindrom ini mengenai kulit, selaput lendir orifisium, dan mata dengan keadaan umum bervariasi dari ringan sampai berat. Meskipun kasusnya jarang terjadi, SSJ memiliki dampak yang signifikan terhadap kesehatan masyarakat karena angka morbiditas dan mortalitas yang tinggi. Tujuan penelitian ini adalah untuk mengetahui beberapa aspek kasus SSJ pasien rawat inap di RSUP Dr. M. Djamil Padang periode Januari 2010 sampai Desember 2011. Penelitian ini dilakukan secara retrospektif dengan menganalisis data rekam medik seluruh pasien SSJ yang dirawat inap. Variabel yang diteliti meliputi jenis kelamin, umur, penyebab SSJ, gejala SSJ, lama rawatan, tingkat keparahan, angka kesembuhan, dan angka mortalitas. Data diolah, dihitung persentasenya, dan disajikan dalam bentuk tabel. Hasil penelitian menunjukkan terdapat 22 kasus SSJ (0,05%) dengan perbandingan insiden pada pria dan wanita adalah 3:1. SSJ banyak terjadi pada umur >19 tahun sampai ≤59 tahun (31,81%) dengan penyebab terbanyak adalah obat (81,82%) terutama obat golongan antikonvulsan (33,33%). Semua pasien mengalami gejala prodromal dan trias kelainan SSJ. Lama rawatan pasien SSJ ≤10 hari. Sebagian besar pasien memiliki tingkat keparahan SSJ yang ringan berdasarkan nilai SCORTEN, yaitu 3,2% dan hampir semua pasien sembuh (95,46%). AbstractStevens-JohnsonSyndrome (SJS) is acute life-threatening mucocutaneous reactions characterized by extensive necrosis and detachment of the epidermis. SSJ comes to the skin, mucous membrane, and the eyes with varies of general state from mild to severe. Although this case is rare, it has a significant public health impact because of high mortality and morbidity. The aim of this study is to know some aspects of SJS cases toward hospitalized patients in Dr. M. Djamil Padang Hospital during January 2010 until December 2011.This study is conducted a retrospective study by analyze the medical record of hospitalized patients with SJS. Variables that were evaluated covered gender, age, causes of SJS, clinical manifestation of SJS, treatment time, the severity, cure rate, and mortality rate. The data were processed, counted the percentage, and presented in tabular form.The result showed there were 22 SJS cases (0,05%) with incidence ratio between male and female was 3:1. SJS most happened in >19 and ≤59 years age group (31,81%) with the most causes was drugs (81,82%) especially anticonvulsant group of drugs (33,33%). All of the patients showed prodromal symptoms and triage abnormalities of SJS. Treatment time for the patients was ≤10 days. A total of 81,82% patients had mild severity based on SCORTEN values, i.e. 3,2% and almost all the patients recovered from SJS (95,46%).

Health services for the elderly need to get special attention, because they are vulnerable for suffering from disease and tend to experience multi-pathology. Some of the health problems of the elderly in Kenagarian Sumaniak had been identified in community service activities before. Aim: The activity aims is to conduct examination and treatment of eye and skin disorders, as also to conduct counseling on the elderly. Methods: The activity is ayes and skin examination and treatment for elderly people in Kenagarian Sumaniak. Furthermore, counseling was also given regarding physical fitness and maintenance of skin health in the elderly. Results: The event was attended by 70 people aged 52-82 years, 28 men and 52 women. The results of the examination found 64 people suffering from eye disorders with diagnoses were dry eyes 24person, immature cataract 16 person and pterygium14 person. Around 52 people suffering from skin disorders with diagnoses were dermatitis 28 person such as dermatitis allergy, numularis, intertriginosa, sebaroid, and chronic). Conclusions: Health problems in the eyes and skin of the elderly identified are mostly overcome with the medicines provided. Some of them are recommended to go to primary health care to get further health services.

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