This paper describes the synthesis, spectral studies and antimicrobial properties of the complexes with the formula [M(C30H24N4O2)Cl2], where M = Fe(II), Co(II), Ni(II), Zn(II) and Cu(II). These complexes were prepared by yield effective template condensation of hexamethylenediamine and 2,2-dihydroxyindane-1,3-dione(ninhydrin). The synthesized complexes were characterized by elemental analysis, infrared spectra, thermogravimetric analysis, Mass spectrum, 13C NMR, molar conductance, electronic spectra, magnetic measurements. TGA and X-ray diffraction studies were used to ascertain the crystal structure and thermal stability of the complexes. The antimicrobial properties of complexes against two Gram-positive bacteria and two Gram-negative bacteria were evaluated by Agar well diffusion technique. Streptomycin and chloramphenicol were taken as standard antibiotics. The results shows that some of the complexes have potential to act as antibacterial agents.
The synthesis, characterization and antimicrobial properties of some novel macro-cyclic complexes with molecular formula [M (C 22 H 16 N 4 O 2 )X]X 2 have been discussed here, where M=Fe (III), Co (III) and Cr (III) and X is either bromine or chlorine. These complexes were prepared by template condensation of Ethylenediamine and 2, 2-dihydroxyindane-1, 3-dione using salts of trivalent metal. The complexes were characterised by physico-chemical techniques such as elemental analysises, molar conductivity, electronic spectra, magnetic moments, mass spectra and IR spectra at CFL, SAIF, Panjab University, Chandigarh. X-ray diffraction data obtained indicates the square pyramidal geometry of Cr(III), Cu (III) and Fe (III) macrocyclic complexes. Thermal stability was determined using the thermogravimetric studies. Agar well diffusion technique was used to check the antimicrobial properties of the prepared macro-cyclic complexes against two Gram +ve Bacteria and two Gram -ve Bacteria. The antimicrobial data on comparison with standard antibiotics such as streptomycin and chloramphenicol supports the antimicrobial behaviour of the above reported cobalt bromide and chromium chloride complexes.
Macrocyclic ligands and their metal complexes are being synthesized very fast as it is a developing area of research in bioinorganic and inorganic chemistry. A new series of trivalent chromium, cobalt and iron complexes have been prepared through template methods with 2, 2-dihydroxyindane-1, 3-dione and isomeric diaminopyridines and effectiveness towards anti fungal properties of these complexes is studied against the cotton plant fungi, Alternaria alternata and Fusarium oxysporum. The complexes have been characterized by elemental analyses, molar conductance, electronic spectra, magnetic measurements and IR spectral data which points towards a distorted octahedral geometry. Conductivity measurements in dimethylsulphoxide indicated them to be 1:2 electrolytic in nature (130-170 ohm -1 cm 2 mol -1 ). Indofil M-45 and bavistin are the standard fungicides which are used to compare the anti-fungicidal properties of the synthesized complexes. Some of the complexes have been found to be antifungal in nature.
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