In view of applications of N-glycosylated compounds in medicinal chemistry and in many other ways,
herein the synthesis of novel N-glycosyl hydrazino carbothioamides is reported. New N-glycosyl
hydrazino carbothioamides were synthesized by the condensation of per-O-acetyl glycosyl
isothiocyanate with different aromatic hydrazides. The newly synthesized compounds were
characterized by using the IR, 1H NMR and mass spectral studies. Antimicrobial evaluation of the
synthesized N-glycosyl hydrazino carbothioamide was also examined. Antimicrobial activities of the
synthesized compound were evaluated against bacteria E. coli, P. aeruginosa, S. aureus, S. pyogenus
and fungi C. albicans, A. niger and A. clavatus. All the N-glycosyl hydrazino carbothioamides exhibit
promising antimicrobial activity.
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