Fungi belonging to Pseudozyma spp. represent a small group of yeasts that have drawn limited interest in the scientific literature. However, new research with one species of Pseudozyma, Pseudozyma flocculosa, has demonstrated the potential of this yeast as a biocontrol agent of plant-pathogenic fungi. Based on recent work, it appears that P. flocculosa, a natural inhabitant of the phyllosphere, possesses unique means of defending its ecological niche by producing unusual extracellular fatty acids that are detrimental to, among other fungi, powdery mildews, an important group of plant pathogens. Results from these studies have shown that the fatty acids naturally insert themselves into powdery mildew fungi and cause disorganization of cellular membranes and cell disintegration. Further work with insertional mutagenesis yielded mutants of P. flocculosa that represent valuable biological tools to better understand the properties of the yeast. For instance, preliminary work with mutants having lost their antagonistic properties has led to the isolation of a new metabolite with antifungal activity. Discoveries pertaining to the ecology and mode of action of P. flocculosa may lead to the study of unique metabolic or biological processes in other Pseudozyma spp. that could well release the untapped potential of these misunderstood yeasts.
This paper documents efforts in Canada, France, Finland, Germany, Hispanoamerica, Israel, Japan, The Netherlands, and Taiwan to disseminate the Model of Human Occupation (MOHO). We aim to characterize the challenges involved, the strategies used, and the impact of these efforts in diverse cultural and social conditions.
Le programme Integrated Psychological Treatment (IPT) de Brenner et al. (1992), d’approche cognitivo-comportementale, a été implanté dans neuf milieux cliniques offrant des services aux personnes souffrant de schizophrénie. Une étude a permis de suivre l’implantation du programme IPT dans chacun des milieux, plus particulièrement d’évaluer le niveau de satisfaction des participants et des intervenants et d’identifier les points forts et les améliorations souhaitées. Les résultats permettent de constater que l’implantation a été un succès pour l’ensemble des neuf milieux. Les intervenants et les participants ont apprécié non seulement la structure hiérarchique qui tient compte davantage des besoins en réadaptation des personnes souffrant de schizophrénie, mais aussi son cadre d’application privilégié qui permet le suivi régulier d’un même groupe de patients pendant une année. Les modifications et ajouts proposés ont permis de développer une version québécoise du programme favorisant davantage l’atteinte des objectifs, particulièrement ceux liés au maintien et à la généralisation des apprentissages dans le contexte de vie réelle des participants.Brenner’s Integrated Psychological Treatment (IPT) program (Brenner et al., 1992 ; Pomini et al., 1998), a cognitive-behavioural approach, was implemented in nine of Quebec’s clinical settings that treat people with schizophrenia. A study allowed an evaluation of the IPT program in each location, with emphasis on the level of satisfaction of both participants and professionals, the program’s strong points, and areas where improvements were needed. The results have shown that the implementation of the program has been successful in all nine clinical settings. Professionals and participants appreciated the IPT program not only for its hierarchic structure that considers the rehabilitation needs of people affected by schizophrenia, but also for its customised application framework, which allows a regular follow-up of a similar group of patients over the course of a one year period. As a result of this study, the modifications proposed and additions have enabled the creation of a Quebec version of the IPT program, which better achieves its objectives, particularly those relating to the maintenance and generalisation of social learning in the context of a participant’s real-life situation.El programa de Tratamiento Psicológico Integral (Integrated Psychological Treatment IPT) de Brenner (Brenner et al., 1992; Pomini et al., 1998), de enfoque cognitivo-comportamental, ha sido implantado en nueve medios clínicos quebequenses que ofrecen servicios a personas que sufren de esquizofrenia. Un estudio ha permitido dar seguimiento a la implantación del programa IPT en cada uno de los medios, en particular, evaluar el nivel de satisfacción de los participantes y de los interventores acerca del programa e identificar los puntos fuertes y las mejoras deseadas. Los resultados permiten constatar que la implantación del programa ha sido un éxito en los nueve medios. Los interventores y los pa...
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