RESUMOA proposta do presente estudo foi investigar os efeitos bioquí-micos da suplementação de carboidratos em uma competição simulada de short duathlon terrestre. A amostra foi constituída de quatorze duatletas, aos quais foram dados suplementos de uma bebida com carboidrato em uma solução a 6% de maltodextrina (g1), placebo (g2) e solução a 6% de glicose (g3), em três momentos distintos da competição simulada: 30 minutos antes da prova (500ml), a cada 15 minutos durante essa competição (200ml) e imediatamente após o término desta (300ml). Amostras de sangue foram coletadas em dois momentos -antes e imediatamente após o final da competição -para análise da glicemia, lactato, insulina e cortisol. Verificaram-se diferenças significativas, em relação aos níveis de glicemia entre g1 e g2, na fase pós-competição. Quando analisado o lactato, também se verificou uma diferença significativa em g1 e g2 na fase durante a competição. Da mesma forma, foram observadas diferenças significativas nas concentrações de cortisol durante a competição (g1) e pós-competição (g2). A conclusão desse estudo, baseada nos dados obtidos das amostras sanguíneas, foi que a suplementação de maltodextrina fornece indicativos bioquímicos que favorecem sua utilização em competições como o short duathlon terrestre.Palavras-chave: carboidratos, competição, glicose, lactato, insulina, cortisol. ABSTRACT Biochemical Effects of Carbohydrates Supplementation in a Simulated Short Land Duathlon Competition This study aimed to investigate the biochemical effects of carbohydrates supplementation in a simulated short land duathlon competition. Sample size consisted of 14 athletes that ingested supplements of a 6% maltodextrin solution (G1), placebo (G2), and a 6% glucose solution (G3), in three different moments of the simulated competition: 30 min before de competition (500ml), every 15 min during the competition (200ml), and immediately after the end of the competition (300ml).Blood sampling was obtained during two stages of the competitionbefore and immediately after the end -to blood glucose, lactate, insulin and cortisol analyses. We found significant differences at glucose concentrations between G1 and G2 after competition. When lactate concentrations were analysed, it was also found a significant difference in G1 and G2 during the competition, as well, in the cortisol concentrations during the competition (G1) and after competition (G2). We conclude that the maltodextrin supplementation provides biochemical evidence that favors its ingestion in simulated short land duathlon competition.
The purpose of the present study was to investigate the biochemical effects of carbohydrate supplementation in a simulated competition of short terrestrial duathlon. Ten duathletes participated in a simulated competition of short terrestrial duathlon 30 minutes after the ingestion of a 6% (30g/500ml) maltodextrin solution (MALT) or a placebo (PLA). This solution was also ingested every 15 minutes during the competition (12g/200ml); and immediately after the competition (18g/300ml). Samples of blood were collected at 3 time points: 1) at rest 1 hour before the beginning of the competition; 2) during the competition (approximately 1 hour and 45 minutes after the 1st collection); 3) immediately after the competition. Blood was analyzed for blood glucose, lactate, insulin and cortisol. Significant differences were observed in relation to blood glucose levels between MALT and PLA in the post-competition phase. There was also a significant difference in the lactate levels observed between MALT and PLA during the competition phase. Similarly, a significant difference in the cortisol concentrations during and after the competition phases (MALT and PLA) were observed. We conclude that maltodextrin supplementation appears to be beneficial during short terrestrial duathlon competition as evidenced by biochemical markers.
We investigated the effect of fish oil (FO) supplementation on tumor growth, cyclooxygenase 2 (COX-2), peroxisome proliferator-activated receptor gamma (PPARγ), and RelA gene and protein expression in Walker 256 tumor-bearing rats. Male Wistar rats (70 days old) were fed with regular chow (group W) or chow supplemented with 1 g/kg body weight FO daily (group WFO) until they reached 100 days of age. Both groups were then inoculated with a suspension of Walker 256 ascitic tumor cells (3×107 cells/mL). After 14 days the rats were killed, total RNA was isolated from the tumor tissue, and relative mRNA expression was measured using the 2-ΔΔCT method. FO significantly decreased tumor growth (W=13.18±1.58 vs WFO=5.40±0.88 g, P<0.05). FO supplementation also resulted in a significant decrease in COX-2 (W=100.1±1.62 vs WFO=59.39±5.53, P<0.001) and PPARγ (W=100.4±1.04 vs WFO=88.22±1.46, P<0.05) protein expression. Relative mRNA expression was W=1.06±0.022 vs WFO=0.31±0.04 (P<0.001) for COX-2, W=1.08±0.02 vs WFO=0.52±0.08 (P<0.001) for PPARγ, and W=1.04±0.02 vs WFO=0.82±0.04 (P<0.05) for RelA. FO reduced tumor growth by attenuating inflammatory gene expression associated with carcinogenesis.
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