ABO is a safe, effective alternative to ONA in treating crow's feet wrinkles.

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This retrospective study was designed to evaluate the efficacy and safety of simultaneous topography-guided PRK plus cross linking for patients with mild to moderate keratoconus and to evaluate the stability of the cone. The patients were evaluated over two years for the progression and stability of the cone by the Allegro Pentacam Oculyzer to assess the changes of corneal curvatures (K readings) and the stability of the cone after the surgery and evaluating uncorrected distance (UDVA) and best corrected (CDVA) visual acuities. The follow-up results showed that UDVA improved from 0.4±0.3 to 0.7±0.1 and CDVA changed from 0.6±0.1 to 0.8±0.1 (P < 0.001). The keratometry value decreased from 44.1±2.2 to 41.4±1.6 D for K1, and from 46.4±2.6 to 43.5±1.7 for K2 (P < 0.001). This combined procedure offers a promising method to stabilize the corneal surface with reducing higher order aberrations so enhancing quality of vision in keratoconus patients.

Background Retinopathy is a common and specific microvascular complication of diabetes. Clinical and experimental findings suggested that choroidal vasculopathy in diabetes may play a role in the pathogenesis of diabetic retinopathy. Spectral-domain optical coherence tomography (SD-OCT) can analyze choroidal structure and histopathological changes in diabetes. Purpose To compare choroidal thickness (CT) before and after panretinal photocoagulation (PRP), modified grid laser (MGP) and combined (panretinal photocoagulation & modified gird laser) using SD-OCT. Design Comparative prospective non-randomized case study, included 30 eyes of 30 patients from both sexes aging from 15 to 60 years. All patients were from Ain-Shams University Hospitals outpatient clinics. Patients were divided into 3 equal groups: Group A Patients with PDR underwent PRP, Group B: Patients with macular edema (ME) underwent MGP, Group C: Patients with PDR&ME underwent combined (PRP & MGP). All cases underwent SD-OCT with CT measurement before and at 1 & 3 Mns after laser therapy with assessment of best corrected visual acuity (BCVA). Results Mean age of participant was 50.83 ± 5.34 (SD). The mean CT in group A at baseline was 329.00 ± 36.08 μm (SD). This was increased to 336.40 ± 35.64 μm at 1 month then was decreased to 309.10 ± 38.87 μm at 3 Mns after laser therapy. This was showed highly statistically significant difference (P-value = 0.000). In group B the CT at baseline was 328.90 ± 19.69 μm. This was decreased to 313.90 ± 17.83 μm & 288.90 ± 23.10 μm after 1 & 3 months respectively with highly statistically significant difference (P-value = 0.000). While in group C the mean CT at baseline 329.80 ± 21.06 μm. This was decreased to 318.10 ± 19.25 μm, 300.40 ± 17.98 μm at 1 & 3 months after combined laser respectively. This was showed highly statistically significant difference (P-value = 0.000). There was no statistically significant difference between the studied groups regarding preoperative and postoperative (after 1&3 Mns) CT. There was no statistically significant difference observed between the studied groups regarding preoperative BCVA (P-value = 0.437). While P-value showing highly statistically significant difference between the studied groups regarding postoperative BCVA (P-value = 0.000). Conclusion The Choroidal thickness decreased in all 3 studied groups; suggesting that all laser techniques may reduce choroidal vascular permeability or cause atrophy of choroidal vessels over a 12-week period.

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