A straightforward method for the synthesis of tetrahydrodiazepinones (III) can be optimized using microwave irradiation. The products are easily converted to the hexahydro derivatives (V). -(WLODARCZYK, N.; GILLERON, P.; MILLET, R.; HOUSSIN, R.; HENICHART*, J.-P.; Tetrahedron Lett. 48 (2007) 14, 2583-2586; Inst. Chim. Pharm. Albert Lespagnol, Univ. Lille 2, F-59006 Lille, Fr.; Eng.) -Mais 29-149
A Versatile and Efficient Synthesis of 3-Aroyl-1,4-dihydroquinolin-4-ones. -The title reaction involves a Michael-type addition of β-ketonic enol ethers with methyl anthranilate followed by base-promoted cyclization. -(STERN, E.; MILLET, R.; DEPREUX*, P.; HENICHART, J.-P.; Tetrahedron Lett. 45 (2004) 50, 9257-9259; Inst. Chim. Pharm., Univ. Lille, F-59006 Lille, Fr.; Eng.) -Mais 13-153
Synthesis. -The simple and efficient synthesis of substituted pyridones from dicarbonylallene (I) can be performed in two distinct steps, allowing the possibility to introduce different substituents in the positions 1 and 4. Under water-free conditions the yields are generally excellent. With the o-aminopyridine (VI), a new pyridopyrimidone is obtained instead of the expected pyridine (IX). -(BOISSE, T.; RIGO*, B.; MILLET, R.; HENICHART, J.-P.; Tetrahedron 63 (2007) 42, 10511-10520; Lab. Synth. Org., Ec. Hautes Etud. Ind., F-59046 Lille, Fr.; Eng.) -Bartels 05-142
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