ChemInform Abstract: From Dicarbonylallene to 1‐Aryl‐3,6‐dimethyl‐4‐aminoaryl‐2‐pyridones: A One‐Pot Versatile and Uncatalyzed Synthesis.

Abstract

Synthesis. -The simple and efficient synthesis of substituted pyridones from dicarbonylallene (I) can be performed in two distinct steps, allowing the possibility to introduce different substituents in the positions 1 and 4. Under water-free conditions the yields are generally excellent. With the o-aminopyridine (VI), a new pyridopyrimidone is obtained instead of the expected pyridine (IX). -(BOISSE, T.; RIGO*, B.; MILLET, R.; HENICHART, J.-P.; Tetrahedron 63 (2007) 42, 10511-10520; Lab. Synth. Org., Ec. Hautes Etud. Ind., F-59046 Lille, Fr.; Eng.) -Bartels 05-142